Generic:

Zox 500mg Tablet contains Nitazoxanide, an antiprotozoal agent used primarily for the treatment of parasitic infections like Cryptosporidiosis and Giardiasis. It belongs to Square Pharmaceuticals Ltd.

Description:

Zox 500mg Tablet is an antiparasitic medication designed to treat diarrhea caused by infections such as Cryptosporidium parvum and Giardia lamblia. The active ingredient, Nitazoxanide, interferes with the anaerobic energy metabolism of parasites, thus inhibiting their growth and alleviating symptoms.

Benefits:

• Effective against a variety of parasitic infections.
• Reduces symptoms of diarrhea caused by protozoal infections.
• Well tolerated with mild, transient side effects.
• Can be used for children and adults.

Ingredients:

Each Zox tablet contains 500mg of Nitazoxanide as the active ingredient.

Uses and Doses:

• For adults and children above 12 years: 1 tablet (500mg) every 12 hours for 3 days.
• Children 1-3 years: 5ml suspension every 12 hours for 3 days.
• Children 4-11 years: 10ml suspension every 12 hours for 3 days.
• It should be taken with food.

Side Effects:

Common side effects include headache, nausea, vomiting, abdominal pain, dizziness, and discolored urine. Other rare side effects may include increased creatinine, enlarged salivary glands, pruritus, and rhinitis.

How to Use:

Take this tablet orally, preferably with food, as prescribed by your doctor. Swallow it whole or, if necessary, crush it and take it with a full glass of water. Complete the full course of medication even if symptoms improve early.

Pregnancy & Lactation:

Zox 500mg is classified as a Category B medication by the FDA. Although no well-controlled studies have been conducted on pregnant women, it should only be used if necessary during pregnancy. Caution is advised when used during lactation as it can pass into breast milk.

Precautions and Warnings:

• Use with caution in patients with hepatic or renal impairment.
• Do not use if allergic to Nitazoxanide.
• Inform your doctor if you're pregnant or breastfeeding before taking this medication.
• Avoid using it if you are on other highly plasma protein-bound drugs.

Safety Information:

Monitor liver function and blood tests while on this medication. Do not stop taking the medicine early, as it may increase the risk of reinfection.

Indications:

Used for the treatment of parasitic infections like Cryptosporidiosis and Giardiasis that cause diarrhea.

Pharmacology:

Nitazoxanide works by inhibiting the pyruvate-ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer, disrupting the energy metabolism of parasites.

Therapeutic Class:

Anti-diarrhoeal Antiprotozoal

Storage Conditions:

Store below 30°C in a cool, dry place away from light and moisture. Keep out of reach of children.

3 FAQ:

1. Can Zox 500mg be used during pregnancy?
   It is classified as Category B but should only be used if necessary during pregnancy.
2. What should I do if I miss a dose?
   Take the missed dose as soon as you remember, but do not double up the next dose.
3. How long does it take for Zox to work?
   You may begin feeling better after a few doses, but complete the full treatment for full effectiveness.

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