Generic
Meropenem Trihydrate 500mg

Description
Meropen-IV 500 is a carbapenem antibiotic for parenteral use. It is effective against Gram-positive, Gram-negative, aerobic, and anaerobic bacterial infections.

Benefits
Meropenem provides potent bactericidal action for treating severe infections such as pneumonia, intra-abdominal infections, meningitis, septicemia, and pulmonary infections in cystic fibrosis patients.

Ingredients
Active Ingredient: Meropenem Trihydrate 500mg/vial

Uses and Doses
Meropenem is prescribed for conditions like pneumonia, urinary tract infections, gynecological infections, skin and soft tissue infections, meningitis, septicemia, and febrile neutropenia.
Adults are typically given 500 mg to 1 g intravenously every 8 hours, with the dose adjusted based on infection severity. For children, doses range from 10 to 40 mg/kg every 8 hours.

Side Effects
Common side effects include inflammation, thrombophlebitis, rash, nausea, vomiting, diarrhea, headache, and injection site reactions.

How to Use
Administer Meropenem intravenously over 30-120 minutes as prescribed. Properly reconstitute the vial and adhere to dosage schedules for maximum efficacy.

Pregnancy & Lactation
Classified as pregnancy category B, Meropenem should be used during pregnancy only if necessary. Caution is advised for nursing mothers, as the drug may be excreted in breast milk.

Precautions and Warnings
Discontinue use immediately if an allergic reaction occurs. Use caution in patients with hepatic conditions, monitoring transaminase and bilirubin levels. Avoid concurrent use with probenecid or valproic acid.

Safety Information
Store below 30°C in a cool, dry, and light-protected place. Keep children out of reach and ensure proper disposal of unused medication.

Indications
Meropenem is indicated for treating severe bacterial infections, including pneumonia, intra-abdominal infections, septicemia, meningitis, and pulmonary infections associated with cystic fibrosis.

Pharmacology
Meropenem inhibits bacterial cell wall synthesis by acting on penicillin-binding proteins (PBPs), providing broad-spectrum bactericidal activity.

Therapeutic Class
Other Beta-Lactam Antibiotics

Storage Conditions
Store at temperatures below 30°C in a dry, light-protected area. Keep out of children’s reach for safety.

3 FAQ

1. Can Meropenem be used in children?
   It is safe for children over three months old, with doses tailored to weight and infection type.
2. What should I do if I miss a dose?
   Consult your healthcare provider. Do not double the dose to make up for a missed one.
3. Is Meropenem effective for multidrug-resistant infections?
   Yes, Meropenem is effective against many multidrug-resistant Gram-positive and Gram-negative bacteria.

Disclaimer
This information is for educational purposes only. Always consult a healthcare provider for personalized medical advice and treatment recommendations.

Keywords: Meropenem, Renata Pharma, carbapenem antibiotic, nosocomial pneumonia, intra-abdominal infections, bacterial infections, multidrug resistance, septicemia, meningitis, cystic fibrosis, febrile neutropenia, skin infections, gynecological infections, broad-spectrum antibiotic, IV antibiotic, pediatric dosage, bacterial cell wall inhibition, transaminase monitoring, injection site reactions, Gram-negative bacteria.