Generic
Meropenem Trihydrate

Description
Meropen-IV 1 is a carbapenem antibiotic used for treating a wide range of severe bacterial infections. Its broad-spectrum activity makes it effective against Gram-positive, Gram-negative, and anaerobic bacteria.

Benefits
Meropenem has potent bactericidal activity against conditions such as nosocomial pneumonia, intra-abdominal infections, meningitis, septicemia, and cystic fibrosis-related pulmonary infections. It is also highly effective against multidrug-resistant bacteria.

Ingredients
Active Ingredient: Meropenem Trihydrate 1g/vial

Uses and Doses
Meropenem treats infections, including pneumonia, urinary tract infections, gynecological infections, skin infections, meningitis, septicemia, and febrile neutropenia.
The typical dose for adults is 500 mg to 2 g intravenously every 8 hours, depending on the severity of the infection. For children, doses range from 10 to 40 mg/kg every 8 hours, with adjustments based on body weight and age.

Side Effects
Common side effects include injection site reactions, rash, nausea, vomiting, diarrhea, headache, and thrombophlebitis. Severe allergic reactions are rare but may occur.

How to Use
Meropenem is administered intravenously over 30-120 minutes. The suspension should be prepared and stored as directed. Follow the prescribed dosage schedule for optimal results.

Pregnancy & Lactation
Classified as pregnancy category B, Meropenem should only be used if necessary during pregnancy. Caution is advised while breastfeeding, as many medications are excreted in breast milk.

Precautions and Warnings
Discontinue use immediately if an allergic reaction occurs. Use cautiously in patients with hepatic disease, regularly monitoring transaminase and bilirubin levels. Avoid combining with drugs like probenecid, which can alter Meropenem’s excretion.

Safety Information
Store below 30°C in a cool, dry, and light-protected environment. Keep out of children’s reach and properly dispose of unused medication.

Indications
Meropenem is indicated for pneumonia, intra-abdominal infections, meningitis, gynecological infections, septicemia, skin infections, cystic fibrosis pulmonary infections, and febrile neutropenia.

Pharmacology
Meropenem is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis, exerting bactericidal activity. Its stability against beta-lactamase enzymes enhances its efficacy against resistant bacterial strains.

Therapeutic Class
Other Beta-Lactam Antibiotics

Storage Conditions
Store at temperatures below 30°C in a dry, light-protected area. To ensure safety, keep out of children’s reach.

3 FAQ

1. Can Meropenem be used in children?
   It is used in children over three months old, with doses adjusted by weight and infection severity.
2. What should I do if I miss a dose?
   Contact your healthcare provider for advice. Do not double the dose to make up for a missed dose.
3. Can Meropenem treat multidrug-resistant infections?
   Yes, it is effective against many multidrug-resistant Gram-positive and Gram-negative bacteria.

Disclaimer
This information is provided for educational purposes only. Consult a healthcare professional for specific medical advice and treatment recommendations.

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