Generic: Miconazole Nitrate 2% w/w

Description: Gelora Oral Gel, manufactured by Square Pharmaceuticals Limited, contains the active ingredient Miconazole Nitrate (2% w/w). It is an antifungal medication designed to treat oral and gastrointestinal candidiasis and fungal infections in the mouth, throat, and gut.

Benefits:

• Effective against fungal infections, especially candidiasis
• Target superinfections caused by gram-positive bacteria
• Works by disrupting the fungal cell membrane, causing cell death
• Treats both localized and systemic fungal infections

Ingredients:

• Active Ingredient: Miconazole Nitrate (2% w/w)
• Other components: as listed in the leaflet provided by the manufacturer

Uses and Doses: Gelora Oral Gel is prescribed to treat oral thrush, gastrointestinal candidiasis, and fungal infections in the mouth and throat.

• Infants (4-24 months): 1.25 ml (¼ spoon) 4 times a day after meals.
• Adults and children (2+ years): 2.5 ml (½ spoon) 4 times a day after meals.
• For gastrointestinal candidiasis: 20 mg/kg/day in divided doses, not exceeding 250 mg (10 ml gel) 4 times a day.

Side Effects:

• Nausea
• Vomiting
• Diarrhea (long-term use)
• Allergic reactions (rare)

How to Use: Apply a small amount of Gelora Gel directly to the affected area in the mouth using a clean finger. For best results, keep the gel in contact with the affected area as long as possible. Remove dental prosthetics at night and brush them with the gel. Continue using the gel for at least one week after symptoms disappear.

Pregnancy & Lactation: The safety of Gelora Gel during pregnancy has not been established, and it should be used with caution. If breastfeeding, consult a doctor before use.

Precautions and Warnings:

• Monitor the anticoagulant effect if taken with anticoagulants.
• Ensure the gel does not obstruct the throat in infants.
• Avoid using in patients with known hypersensitivity to the components.
• May interact with medications like Phenytoin, Cyclosporine, and Cisapride.

Safety Information: Use Gelora Gel as prescribed. Do not exceed the recommended dose, and avoid contact with the eyes, nose, or mouth.

Indications:

• Oropharyngeal candidiasis
• Gastrointestinal candidiasis
• Fungal infections of the mouth and throat

Pharmacology: Miconazole disrupts ergosterol biosynthesis, a key component of the fungal cell membrane, causing leakage and cell death. It also exhibits antibacterial action against gram-positive bacteria.

Therapeutic Class: Aural Antifungal preparations

Storage Conditions: Store in a cool, dry place away from light and heat. Keep out of reach of children.

3 FAQs:

1. How long should I use Gelora Gel for oral candidiasis? Use the gel for at least one week after symptoms disappear, or as directed by your doctor.
2. Can Gelora Gel be used during pregnancy? Use only if necessary, and consult your doctor to weigh the risks and benefits.
3. Are there any interactions with other medications? Yes, Miconazole can interact with drugs like warfarin, Phenytoin, and others. Inform your doctor about all medications you're taking.

Disclaimer:

This information is for general purposes only and is not intended to replace professional medical advice. Always consult your healthcare provider for any questions or concerns regarding medications.

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