Generic
Linagliptin and Metformin Hydrochloride combination, used for managing type 2 diabetes mellitus.

Description
Lino-M 500 is a prescription medication from Acme Laboratories Ltd, combining 2.5mg of Linagliptin and 500mg of Metformin Hydrochloride per tablet. It effectively controls blood sugar when used alongside a balanced diet and exercise.

Benefits
Lino-M 500 helps in lowering blood sugar levels, which can prevent diabetes complications like kidney damage, blindness, and cardiovascular issues.

Ingredients
Each tablet contains 2.5mg Linagliptin and 500mg Metformin Hydrochloride.

Uses and Doses
The dosage is individualized, with the maximum recommended dose being 2.5 mg of Linagliptin and 1000 mg of Metformin twice daily with meals. Extended-release tablets are taken once daily with a meal, up to a maximum of 5 mg of Linagliptin and 2000 mg of Metformin.

Side Effects
Common side effects include diarrhea, nausea, vomiting, headache, nasal congestion, and potential hypoglycemia, especially when combined with other diabetes medications.

How to Use
Take as prescribed by your doctor, usually with meals to minimize gastrointestinal issues. Do not chew or crush the tablets.

Pregnancy & Lactation
Lino-M 500 should only be used during pregnancy or lactation if necessary, as there are limited studies on safety.

Precautions and Warnings
Use cautiously if you have renal impairment, hepatic issues, pancreatitis, or if undergoing surgery. Avoid alcohol and keep hydrated to prevent lactic acidosis.

Safety Information
Monitor blood sugar levels regularly. Avoid use if you have a history of metabolic acidosis or severe renal impairment.

Indications
For adult patients with type 2 diabetes mellitus needing additional glycemic control.

Pharmacology
Linagliptin inhibits DPP-4, which degrades GLP-1 and GIP hormones, increasing insulin secretion and decreasing glucagon. Metformin lowers glucose production in the liver and improves insulin sensitivity.

Therapeutic Class
Combination oral hypoglycemic agents.

Storage Conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.

FAQs

1. What should I do if I miss a dose?
   Take it as soon as you remember unless it’s almost time for the next dose.
2. Is Lino-M 500 safe with other diabetes medications?
   Hypoglycemia risk increases with certain medications; consult your doctor.
3. Can I drink alcohol while on Lino-M 500?
   Alcohol is not recommended as it may increase the risk of low blood sugar and lactic acidosis.

Disclaimer

This information does not replace professional medical advice. Always follow your healthcare provider’s instructions.

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