Generic

Azithromycin 500mg

Description

Zimax 500 is a potent antibiotic tablet manufactured by Square Pharmaceuticals Limited. It is primarily composed of Azithromycin, a broad-spectrum antibiotic effective against various bacterial infections. Azithromycin works by inhibiting protein synthesis in bacteria, preventing their growth and multiplication. The tablet is known for its high tissue concentration and long half-life, making it effective with shorter treatment durations.

Benefits

Zimax 500 offers several benefits, including its broad-spectrum activity against many gram-positive and gram-negative bacteria. It is effective in treating respiratory tract infections, skin infections, sexually transmitted diseases, and more. Its extended tissue penetration ensures prolonged antibacterial effects even after the medication is discontinued. Additionally, its convenient dosing schedule enhances patient compliance.

Ingredients

• Active Ingredient: Azithromycin 500mg
• Inactive Ingredients: Lactose, magnesium stearate, microcrystalline cellulose, and other excipients.

Uses and Doses

Zimax 500 is used to treat a variety of bacterial infections including respiratory tract infections (bronchitis, pneumonia), ear infections (otitis media), skin infections, and sexually transmitted diseases like non-gonococcal urethritis and cervicitis.

• Adults: 500 mg once daily for 3 days or as a single 1g dose for specific infections.
• Children: Dosage varies based on body weight, typically 10 mg/kg once daily for 3 days.
• For typhoid fever: 500 mg daily for 7-10 days.
• IV Therapy: Used in severe cases requiring hospital treatment, followed by oral therapy.

Side Effects

Common side effects of Zimax 500 include nausea, vomiting, stomach discomfort, diarrhea, and headaches. Less frequently, patients may experience dizziness, skin rashes, and flatulence. Severe allergic reactions are rare but can include itching, swelling, and difficulty breathing. If any adverse effects persist or worsen, medical attention should be sought promptly.

How to Use

Take Zimax 500 tablets orally, preferably on an empty stomach, either 1 hour before or 2 hours after meals. Swallow the tablet whole with a glass of water. It is crucial to adhere to the prescribed dosage schedule and complete the full course of treatment to avoid the risk of bacterial resistance and recurrence of infection.

Pregnancy & Lactation

Zimax 500 falls under Pregnancy Category B, indicating no known risk to the fetus in animal studies, but sufficient human studies are lacking. It should be used during pregnancy only if clearly needed. Caution is advised when administering to breastfeeding women as the drug's effects on the infant are not fully known. Consult a healthcare provider before use.

Precautions and Warnings

Patients with known allergies to Azithromycin or other macrolide antibiotics should avoid Zimax 500. Caution is advised in patients with liver or kidney impairment. It should not be used concurrently with ergot derivatives. Regular monitoring is recommended to prevent superinfections and manage any adverse effects that may arise.

Safety Information

Zimax 500 should be used under medical supervision, with adherence to prescribed doses and duration. Avoid taking antacids within two hours of the medication. Inform your doctor of any pre-existing conditions, especially heart-related issues, as Azithromycin can prolong the QT interval in some patients. Report any unusual symptoms or side effects to your healthcare provider immediately.

Indications

Zimax 500 is indicated for the treatment of bacterial infections, including:

• Respiratory tract infections like bronchitis and pneumonia
• Ear infections (otitis media)
• Skin and soft tissue infections
• Non-gonococcal urethritis and cervicitis caused by Chlamydia trachomatis
• Pharyngitis/tonsillitis and sinusitis
• Typhoid fever and some sexually transmitted diseases

Pharmacology

Azithromycin in Zimax 500 is acid-stable, allowing for effective oral administration. It achieves high tissue concentrations and is actively transported to infection sites, where it is released during phagocytosis. It has a long half-life, enabling sustained bacteriostatic levels with once-daily dosing. The drug is primarily excreted unchanged via bile and to a lesser extent in urine.

Therapeutic Class

Macrolide Antibiotics

Storage Conditions

Store Zimax 500 in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children. Ensure the bottle is tightly closed when not in use. The oral suspension, once reconstituted, should be kept refrigerated and used within 10 days.

FAQs

1. What infections does Zimax 500 treat?
   • Zimax 500 is used to treat various bacterial infections, including respiratory, ear, skin, and sexually transmitted infections.
2. Can I take Zimax 500 with food?
   • It is recommended to take Zimax 500 on an empty stomach for better absorption, either 1 hour before or 2 hours after meals.
3. What should I do if I miss a dose?
   • If you miss a dose of Zimax 500, take it as soon as you remember. If it's close to your next dose, skip the missed dose and continue with your regular schedule. Do not double up the dose.

Disclaimer

The information provided is for educational purposes and should not replace professional medical advice. Always consult your healthcare provider for personalized guidance regarding your health and treatment options.

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