Generic

Sucralfate – the active ingredient in Sucrasol Oral Suspension, at a strength of 1 gm per 5 ml.

Description

Sucrasol Oral Suspension is a gastro-protective medication formulated to treat duodenal ulcers, gastric ulcers, chronic gastritis, and to prevent gastrointestinal bleeding due to stress ulcers in critically ill patients. Sucralfate’s unique action mechanism forms a protective barrier over the ulcer site, encouraging healing and protecting the affected area.

Benefits

Sucrasol offers relief from gastrointestinal ulcers and reduces the risk of bleeding in high-stress patients, while its minimal absorption in the bloodstream minimizes systemic effects. Additionally, Sucrasol protects against bile acid damage and aids in healing, especially in patients with chronic gastritis.

Ingredients

The primary active ingredient in Sucrasol is Sucralfate at a concentration of 1 gram per 5 ml. It is available in a 200 ml bottle formulation.

Uses and Doses

For adults and adolescents over 14, Sucrasol is administered to treat duodenal ulcers, gastric ulcers, and chronic gastritis. The usual dose for duodenal and gastric ulcers is 2 gm twice daily or 1 gm four times daily, while stress ulcer prophylaxis in critically ill patients is 1 gm administered four to six times daily. Pediatric use under 14 is not established. Elderly patients should use the lowest effective dose.

Side Effects

Common side effects include headache, nausea, abdominal pain, constipation, diarrhea, and urticaria. Rare cases of bezoar formation have been reported, particularly in patients with conditions leading to delayed gastric emptying. Diabetic patients may experience hyperglycemia.

How to Use

Sucrasol should be taken on an empty stomach, ideally 1 hour before meals or at bedtime. Antacids should not be taken within 30 minutes of Sucrasol administration.

Pregnancy & Lactation

There is no established safety profile of Sucrasol for pregnant women. It should only be used during pregnancy if absolutely necessary, and caution is recommended during breastfeeding due to uncertain excretion into human milk.

Precautions and Warnings

Use Sucrasol with caution in patients with renal dysfunction, as it may increase aluminum absorption and cause toxicity. Sucrasol should be avoided in patients on dialysis and those with chronic renal impairment. Caution is also advised for patients predisposed to bezoar formation, such as those with delayed gastric emptying or using enteral feeding.

Safety Information

Patients should avoid driving or operating machinery if they experience dizziness or drowsiness after taking Sucrasol.

Indications

Sucrasol is indicated for:

• Duodenal ulcers
• Gastric ulcers
• Chronic gastritis
• Stress ulceration prevention in critically ill patients

Pharmacology

Sucralfate works by forming a complex with ulcer sites, creating a physical barrier that shields the affected area from stomach acids, pepsin, and bile. It minimizes systemic absorption, with trace amounts eliminated through urine.

Therapeutic Class

Sucrasol belongs to the therapeutic class of Chelating Complexes.

Storage Conditions

Store Sucrasol in a cool, dry place, protected from light to preserve its effectiveness.

FAQ

1. Can I take Sucrasol with other medications?
   Sucrasol may interfere with certain medications, so allow a two-hour window between other drugs.
2. Can I use Sucrasol if I am pregnant?
   The safety of Sucrasol in pregnancy is not well-established. Consult your doctor before use.
3. How long should I use Sucrasol?
   Treatment duration varies by condition, with ulcer treatment lasting up to 12 weeks if necessary. Stress ulcer prophylaxis should not exceed 14 days without consultation.

Disclaimer

This information is for educational purposes and does not replace medical advice. Always follow your healthcare provider’s guidance when taking any medication.

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