Generic
Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used to alleviate symptoms of osteoarthritis and rheumatoid arthritis.

Description
Nabumetone is a non-selective cyclooxygenase (COX) inhibitor, effective in managing inflammation, pain, and joint discomfort in arthritis.

Benefits
Nabumetone helps reduce pain, inflammation, and stiffness associated with osteoarthritis and rheumatoid arthritis, enabling improved mobility and quality of life.

Ingredients
Active ingredient: Nabumetone 500 mg. Inactive excipients may vary depending on the formulation.

Uses and Doses
For adults, the starting dose is 1,000 mg daily, taken with or without food. For greater symptom relief, some patients may require up to 1,500-2,000 mg daily in one or two doses.

Side Effects
Common side effects include diarrhea, dyspepsia, abdominal pain, constipation, nausea, and dry mouth. Serious reactions like allergic reactions and gastrointestinal issues can occur.

How to Use
Take Nabumetone orally as directed by a physician. Adhere to prescribed doses to maximize benefits and minimize risks.

Pregnancy & Lactation
Pregnancy Category C: Use Nabumetone during pregnancy only if the potential benefit outweighs the risks. Limited studies indicate no developmental abnormalities, but safety for humans is not fully established.

Precautions and Warnings
Nabumetone is not a substitute for corticosteroids and may not treat corticosteroid deficiency. Patients discontinuing corticosteroids should taper slowly.

Safety Information
Do not use Nabumetone if you have hypersensitivity to NSAIDs. Use cautiously if taking ACE inhibitors, as NSAIDs may reduce their antihypertensive effects.

Indications
Nabumetone is indicated for the treatment of pain and inflammation associated with osteoarthritis and rheumatoid arthritis.

Pharmacology
Nabumetone inhibits prostaglandin G/H synthase (COX-1 and COX-2), reducing inflammation and pain. It acts by blocking prostaglandin synthesis, which mediates inflammation and pain in the body.

Therapeutic Class
Drugs for Rheumatoid Arthritis, Drugs for Osteoarthritis

Storage Conditions
Store Nabumetone at 25°C with excursions allowed between 15-30°C in a tightly sealed, light-resistant container.

FAQs

1. What is Nabumetone used for? Nabumetone is used to treat pain and inflammation in osteoarthritis and rheumatoid arthritis.
2. How should Nabumetone be taken? Take as directed by a healthcare provider, usually at a starting dose of 1,000 mg.
3. Can Nabumetone be used during pregnancy? Use Nabumetone during pregnancy only if the benefit outweighs the risks, as data on human safety is limited.

Disclaimer
This summary provides general information about Nabumetone and is not a substitute for professional medical advice. Consult a healthcare provider for advice tailored to your health.

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