Generic:
Aceclofenac 200mg

Description:
Flexivan ER is an extended-release non-steroidal anti-inflammatory drug (NSAID) used for managing pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma, and lumbago. Manufactured by Nipro JMI Pharma Ltd, this formulation ensures prolonged relief with a single daily dose.

Benefits:
Flexivan ER provides long-lasting pain relief by reducing inflammation and swelling. It improves mobility in patients suffering from chronic joint conditions and alleviates pain from injuries and dental procedures. The extended-release formulation allows for convenient once-daily dosing.

Ingredients:
Each tablet contains 200mg of Aceclofenac, a potent cyclooxygenase (COX) inhibitor that blocks prostaglandin synthesis, reducing pain and inflammation.

Uses and Doses:
Flexivan ER is prescribed for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, and trauma-related pain. The recommended dosage for adults is one 200 mg extended-release tablet once daily. Alternatively, a 100 mg tablet can be taken twice daily as directed by a physician.

Side Effects:
Common side effects include nausea, indigestion, diarrhea, abdominal pain, dizziness, and headache. Long-term use may increase the risk of gastrointestinal ulcers, cardiovascular issues, and kidney dysfunction. Rarely, allergic reactions such as skin rash and swelling may occur.

How to Use:
Take one tablet daily with food to minimize gastrointestinal irritation. Swallow the tablet whole with water; do not crush or chew the extended-release formulation. If a dose is missed, take it as soon as remembered unless it is close to the next scheduled dose.

Pregnancy & Lactation:
Flexivan ER should be avoided during pregnancy and lactation unless a physician deems it necessary. Prolonged use may pose risks to fetal development, particularly in the third trimester.

Precautions and Warnings:
Patients with a history of peptic ulcers, gastrointestinal bleeding, liver impairment, renal impairment, or cardiovascular disease should use this medication with caution. Those prone to dizziness should avoid operating heavy machinery or driving.

Safety Information:
Avoid alcohol consumption while using Flexivan ER, as it may increase the risk of gastrointestinal bleeding. Patients taking anticoagulants, diuretics, or methotrexate should consult a doctor before use. A healthcare professional should monitor long-term use.

Indications:
Flexivan ER is indicated for treating pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, and musculoskeletal injuries.

Pharmacology:
Aceclofenac inhibits the cyclooxygenase (COX) enzyme responsible for prostaglandin production, reducing inflammation, pain, and swelling. The extended-release formulation ensures prolonged action, improving patient compliance.

Therapeutic Class:
Drugs for Osteoarthritis, Drugs for Rheumatoid Arthritis, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).

Storage Conditions:
Store in a dry place, away from light and heat. Keep out of the reach of children.

FAQ:
1. Can Flexivan ER be taken on an empty stomach?
It is recommended to take it with food to minimize stomach irritation.

2. Is Flexivan ER suitable for long-term use?
Long-term use should be monitored for potential gastrointestinal and cardiovascular risks under medical supervision.

3. Can Flexivan ER be taken with other pain relievers?
Please consult a doctor before combining it with other NSAIDs or analgesics to avoid potential drug interactions.

Disclaimer:
This information is for educational purposes only. Consult a healthcare provider before using Flexivan ER, particularly if you have pre-existing medical conditions.

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