Famiclav 500 Tablet, manufactured by The ACME Laboratories Ltd, is a potent antibiotic medication that treats infections caused by sensitive bacteria. Its unique combination of Cefuroxime, a second-generation cephalosporin, and Clavulanic Acid, a beta-lactamase inhibitor, provides protection against bacteria resistant to beta-lactam antibiotics. It is highly effective in addressing a variety of bacterial infections.

Benefits

Famiclav 500 is beneficial for treating multiple bacterial infections, particularly those resistant to beta-lactam antibiotics. It is effective in addressing respiratory tract infections, skin infections, and urinary tract infections, as well as severe infections like gonorrhea, pneumonia, and septicemia. This combination ensures a broader range of antibacterial action.

Ingredients

The active ingredients in Famiclav 500 are Cefuroxime Axetil (500mg) and Clavulanic Acid (125mg). Other inactive ingredients may include fillers and binders, depending on the tablet formulation.

Uses and Doses

• Adults and Adolescents (13+ years):
  • Pharyngitis/Tonsillitis: 250mg twice daily for 5-10 days
  • Pneumonia: 250-500mg twice daily for 5-10 days
  • Urinary tract infections: 250mg twice daily for 7-10 days
  • Skin infections: 250-500mg twice daily for 10 days
  • Gonorrhea: 1000mg as a single dose
• Pediatric Patients (3 months to 12 years):
  • Pharyngitis/Tonsillitis: 20 mg/kg/day twice daily for 5-10 days
  • Acute Otitis Media: 30 mg/kg/day twice daily for 10 days

Side Effects

Common side effects include nausea, vomiting, diarrhea, and abdominal pain. Rarely, serious reactions like allergic responses, including rash, angioedema, anaphylaxis, or renal impairment, may occur.

How to Use

Take Famiclav 500 with or without food, as directed by your doctor. Complete the full course of the medication even if symptoms improve early to prevent bacterial resistance.

Pregnancy & Lactation

Use during pregnancy, particularly in the first trimester, should be avoided unless necessary. Cefuroxime and Clavulanic Acid are excreted in small amounts in breast milk, and caution should be taken while breastfeeding.

Precautions and Warnings

Use Famiclav 500 with caution in patients with a history of colitis or those using strong diuretics. Avoid if allergic to cephalosporins. Long-term use can cause overgrowth of resistant microorganisms.

Safety Information

Patients with known cephalosporin allergies or pseudomembranous colitis should avoid taking Famiclav 500. Prolonged usage should be monitored by a healthcare professional to prevent resistance.

Indications

Famiclav 500 is indicated for treating infections like pharyngitis, tonsillitis, acute bacterial otitis media, maxillary sinusitis, pneumonia, bronchitis, skin infections, urinary tract infections, bone and joint infections, septicemia, and uncomplicated gonorrhea.

Pharmacology

Cefuroxime is a bactericidal antibiotic that interferes with bacterial cell wall synthesis, while Clavulanic Acid inhibits beta-lactamase enzymes, allowing Cefuroxime to remain effective against resistant bacterial strains.

Therapeutic Class

Famiclav 500 belongs to the second-generation cephalosporin class of antibiotics.

Storage Conditions

Store the medication in a cool, dry place, below 30°C, away from light and moisture. Keep out of reach of children.

3 FAQ

1. Can I take Famiclav 500 without food?
   Yes, it can be taken with or without food. However, taking it after meals may reduce gastrointestinal discomfort.
2. What should I do if I miss a dose?
   Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your regular schedule.
3. Is Famiclav 500 safe during pregnancy?
   Avoid during the first trimester unless prescribed by a doctor. It can be used later in pregnancy if necessary for treating infections.

Disclaimer

This information is intended for educational purposes only. Consult a healthcare professional for proper diagnosis and treatment.

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