Generic

Ondansetron 8mg

Description

Emistat 8 is an anti-emetic medication containing Ondansetron 8mg, used to prevent and treat nausea and vomiting caused by chemotherapy, radiotherapy, and surgery. It blocks serotonin (5-HT3) receptors, preventing signals that trigger nausea and vomiting in the brain and gut.

Benefits

Emistat 8 is highly effective in controlling nausea and vomiting induced by cancer treatments and post-surgical procedures. It helps improve patient comfort and quality of life during chemotherapy, radiotherapy, and after surgeries.

Ingredients

Each tablet contains Ondansetron 8mg, a selective serotonin (5-HT3) receptor antagonist that prevents nausea and vomiting.

Uses and Doses

Emistat 8 is used to prevent nausea and vomiting due to chemotherapy, radiotherapy, and surgery.

• Chemotherapy-induced nausea and vomiting (CINV):
  • Adults & children (6 months-18 years): 8 mg orally every 8 hours or intravenous (IV) infusion in 3 divided doses (0.15 mg/kg, max 16 mg per dose).
• Radiotherapy-induced nausea and vomiting (RINV):
  • Adults: 8 mg orally 1-2 hours before treatment, then every 8 hours for 5 days.
• Postoperative nausea and postoperative):
  • Adults: 16 mg orally (two 8 mg tablets) or 4 mg IV injection.
  • Pediatrics: 4 mg IV injection (>40 kg) or 0.1 mg/kg IV infusion (<40 kg).

Side Effects

Common side effects include headache, dizziness, diarrhea, constipation, and fever. Rarely, it may cause allergic reactions, bronchospasm, or QT prolongation.

How to Use

Take one tablet orally with water. It can be taken with or without food. For best results, take it before chemotherapy, radiotherapy, or surgery as directed by your doctor.

Pregnancy & Lactation

Emistat 8 is classified as Pregnancy Category B, meaning no known risk in animal studies but limited human data. It is excreted in breast milk, so caution is advised while breastfeeding.

Precautions and Warnings

Patients with a history of hypersensitivity to Ondansetron, severe hepatic impairment, or prolonged QT interval should use Emistat 8 with caution. Avoid combining with Apomorphine, as it may cause severe hypotension and loss of consciousness.

Safety Information

Emistat 8 should be used with caution in patients with heart disease, electrolyte imbalance, or kidney/liver disorders. Do not exceed the prescribed dose, as an overdose may lead to severe dizziness and heart rhythm disturbances.

Indications

Emistat 8 is indicated for:

• Prevention and treatment of nausea and vomiting caused by chemotherapy, radiotherapy, and post-surgical recovery.

Pharmacology

Ondansetron works by blocking serotonin (5-HT3) receptors in the brain and gastrointestinal tract, preventing the activation of vomiting reflexes. It is effective in controlling chemotherapy, radiotherapy, and surgery-induced nausea and vomiting.

Therapeutic Class

Anti-emetic drugs

Storage Conditions

Store below 30ºC in a dry place, protected from light and moisture.

3 FAQ

1. Can Emistat 8 be used for motion sickness?
No, Emistat 8 is not approved for motion sickness. It is precisely for chemotherapy, radiotherapy, and post-surgical nausea and vomiting.

2. How long does Emistat 8 take to work?
It starts working within 30 minutes to 1 hour and provides relief for up to 12 hours.

3. Can I take Emistat 8 on an empty stomach?
Yes, Emistat 8 can be taken with or without food. However, taking it before meals may improve absorption and effectiveness.

Disclaimer

This information is for educational purposes only. Always consult a doctor before using Emistat 8, especially if you have underlying medical conditions or are taking other medications.

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