Generic

Domiren 10 is a tablet containing the active ingredient Domperidone Maleate (10 mg) used to treat digestive conditions related to delayed gastric emptying, nausea, and vomiting.

Description

Domiren 10, manufactured by Renata Pharma Ltd, is a dopamine antagonist that aids in the movement of food through the stomach by enhancing gastrointestinal motility. It prevents nausea, vomiting, and symptoms related to gastroesophageal reflux and delayed gastric emptying.

Benefits

• Eases nausea and vomiting
• Relieves symptoms of bloating, fullness, and abdominal pain
• Enhances gastric motility
• Prevents regurgitation of stomach contents into the esophagus

Ingredients

The active ingredient in Domiren 10 is Domperidone Maleate (10 mg).

Uses and Doses

• Adults: 10-20 mg every 6-8 hours. Max: 80 mg/day
• Children: 2-4 ml suspension per 10 kg body weight every 6-8 hours.
• For nausea and vomiting: 20 mg every 6-8 hours
• Maximum treatment period: 12 weeks

Side Effects

• Hyperprolactinemia (breast soreness, galactorrhea)
• Headache, dry mouth, nervousness
• Diarrhea, rash, itching
• Rare extra-pyramidal reactions

How to Use

Domiren 10 should be taken 15-30 minutes before meals. It may also be taken before bedtime if needed.

Pregnancy & Lactation

Domiren 10 is not recommended during pregnancy. It may be used cautiously during lactation as only small quantities are secreted into breast milk.

Precautions and Warnings

Use with caution in children and patients with hepatic impairment. It should not be used in cases of gastrointestinal hemorrhage or obstruction.

Safety Information

Domiren 10 may interact with antimuscarinics, opioid analgesics, and MAO inhibitors. Do not use if allergic to the drug or if a prolactin-releasing tumor is present.

Indications

• Nausea and vomiting (acute and chronic)
• Gastroesophageal reflux
• Delayed gastric emptying
• Symptoms of bloating, fullness, heartburn

Pharmacology

Domperidone blocks dopamine receptors, primarily in the gastrointestinal tract, promoting smoother digestive motility without affecting the central nervous system, thus minimizing psychotropic effects.

Therapeutic Class

Motility Stimulants, Dopamine Antagonists

Storage Conditions

Store below 30°C, protected from light and moisture. Keep out of children's reach.

3 FAQ

1. How long can I take Domiren 10?
The maximum treatment period is 12 weeks unless directed by a physician.

2. Can children take Domiren 10?
Yes, but with caution. Consult a doctor for the proper dosage based on body weight.

3. Is Domiren 10 safe during pregnancy?
It is not recommended for pregnant women as its safety is not established.

Disclaimer

Always consult a healthcare provider before starting or discontinuing any medication. The information provided is for general knowledge only and is not a substitute for professional advice.

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