Generic

Doximar 200 contains Doxophylline 200 mg, a bronchodilator used to treat COPD, bronchial asthma, and bronchospasms.

Description

Doximar 200 is a methylxanthine derivative that works as a bronchodilator, helping to relax the airways and improve breathing. It primarily treats chronic obstructive pulmonary disease (COPD), bronchial asthma, and bronchospasm. Unlike traditional theophylline, Doxophylline has a better safety profile and reduced effects on the central nervous system and heart.

Benefits

Doximar 200 effectively relieves airway obstruction, reduces inflammation, and improves oxygen flow, making it beneficial for people with asthma and COPD. Compared to other bronchodilators, it has fewer side effects and offers a long-lasting effect, helping to maintain better breathing control throughout the day.

Ingredients

Each tablet contains 200 mg of doxophylline, a selective phosphodiesterase (PDE-4) inhibitor that helps relax the bronchial smooth muscles and reduces inflammatory processes in the lungs.

Uses and Doses

Doximar 200 is used to treat COPD, bronchial asthma, and bronchospasms.

• Adults: 400 mg two or three times daily.
• Elderly patients: 200 mg two or three times daily.
• For children over 12 years, 10 ml of syrup or 200 mg of tablet should be taken twice or thrice daily.
• Children 6-12 years: 6-9 mg/kg body weight twice daily.
• For a 400 mg daily dose: The SR (sustained release) version can be taken once daily.

Side Effects

Common side effects include headache, nausea, vomiting, insomnia, tachycardia, abdominal pain, heartburn, irritability, breathlessness, proteinuria, and hyperglycemia. Severe side effects are rare but should be reported to a doctor immediately.

How to Use

Doximar 200 should be taken with or after meals to reduce gastrointestinal discomfort. Swallow the tablet with a full glass of water and follow the prescribed dosage without exceeding the recommended limit.

Pregnancy & Lactation

Animal studies show that Doxophylline does not harm fetal development, but limited human data exists. It should only be used during pregnancy if the benefits outweigh the risks. Doxophylline is contraindicated during breastfeeding, as its presence in breast milk may affect the infant.

Precautions and Warnings

Patients with liver disease, congestive heart failure, or those on erythromycin, troleandomycin, lincomycin, allopurinol, cimetidine, propranolol, or the anti-flu vaccine should use a lower dose due to potential delays in drug clearance. Smoking, phenytoin, and anticonvulsants may increase clearance, requiring a higher dose in such patients.

Safety Information

Do not take Doximar 200 with other xanthine derivatives, caffeine-containing foods or beverages, or ephedrine, as they may cause toxic reactions. Always follow the prescribed dosage and consult a doctor before combining it with other medications.

Indications

Doximar 200 is indicated for treating COPD, bronchial asthma, and bronchospasms. It helps open airways, improve breathing, and prevent symptoms such as wheezing, coughing, and shortness of breath.

Pharmacology

Doxophylline is a phosphodiesterase (PDE-4) inhibitor that relaxes bronchial smooth muscles and prevents inflammatory processes. Unlike theophylline, it has reduced action on adenosine receptors, leading to fewer cardiovascular and neurological side effects. Additionally, it suppresses platelet-activating factor (PAF) and leukotriene production, which contribute to inflammation in the lungs.

Therapeutic Class

Bronchodilator / Methylxanthine Derivative

Storage Conditions

Store in a cool, dry place away from light and heat. Keep it out of the reach of children.

FAQ

1. Can I take Doximar 200 with food?
It is recommended to take Doximar 200 with or after meals to reduce stomach irritation.

2. How long does Doximar 200 take to work?
It starts working within an hour, and its effects can last several hours, providing long-term symptom relief.

3. Can I take Doximar 200 with coffee or tea?
No, it is best to avoid caffeine-containing products as they may increase side effects.

Disclaimer

This information is for educational purposes only. Always consult a healthcare professional before using Doximar 200, especially if you have underlying health conditions or are pregnant or breastfeeding.

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