Generic

Xinarox 500mg Tablet contains Cefuroxime Axetil 500mg, a second-generation cephalosporin antibiotic.

Description

Xinarox 500mg Tablet is a potent antibiotic used to treat various bacterial infections. It belongs to the second generation of cephalosporins, which are known for their ability to resist beta-lactamase enzymes produced by certain bacteria, making it effective against a wide range of resistant strains.

Benefits

Xinarox 500mg Tablet offers broad-spectrum bactericidal activity, making it effective against many types of bacterial infections. It is especially useful for treating infections that are resistant to other antibiotics, ensuring comprehensive management of bacterial diseases.

Ingredients

The active ingredient in Xinarox 500mg Tablet is Cefuroxime Axetil 500mg. Inactive ingredients include excipients used to formulate the tablet.

Uses and Doses

• Adults and Adolescents (13 years and older): For various infections, including respiratory tract infections, urinary tract infections, and skin infections, the dosage ranges from 250 mg to 500 mg twice daily for 5 to 20 days, depending on the infection type.
• Children (3 months to 12 years): Doses range from 20 mg/kg/day to 30 mg/kg/day in divided doses for different infections.
• Parenteral Administration: Adults may receive 750 mg three times daily via IM or IV injection, with adjustments for severe infections.

Side Effects

Common side effects of Xinarox 500mg Tablet include nausea, vomiting, diarrhea, and skin rashes. Serious side effects, though rare, can include allergic reactions, jaundice, and colitis. Long-term use may lead to overgrowth of non-susceptible organisms such as Candida.

How to Use

Take Xinarox 500mg Tablet exactly as prescribed by your doctor. It can be taken with or without food, but it should be taken at regular intervals to maintain effective levels in the body. Do not skip doses, and complete the full course of treatment even if you feel better.

Pregnancy & Lactation

Cefuroxime, the active ingredient in Xinarox 500mg Tablet, is classified as pregnancy category B. While animal studies have not shown harm, there are no adequate studies in pregnant women. It should be used during pregnancy only if necessary. Cefuroxime is excreted in human milk; hence, caution is advised when administered to breastfeeding mothers.

Precautions and Warnings

Use Xinarox 500mg Tablet with caution in individuals with a history of colitis or those taking powerful diuretics. It can generally be used safely in patients with penicillin hypersensitivity, but cross-reactions have been reported. Monitor renal function in patients with severe renal impairment.

Safety Information

• Allergic Reactions: Seek immediate medical help if you experience rashes, itching, swelling, or difficulty breathing.
• Drug Interactions: Xinarox 500mg may interact with strong diuretics and anticoagulants. Probenecid may increase Cefuroxime levels.
• Driving: This medication may cause dizziness. Avoid driving or operating machinery if you feel unwell.

Indications

Xinarox 500mg Tablet is indicated for the treatment of various bacterial infections including pharyngitis, otitis media, sinusitis, lower respiratory tract infections, urinary tract infections, skin infections, gonorrhea, Lyme disease, and bone and joint infections.

Pharmacology

Cefuroxime, the active component of Xinarox 500mg Tablet, binds to bacterial penicillin-binding proteins, inhibiting cell wall synthesis and leading to bacterial cell death. It remains effective against beta-lactamase-producing bacteria, broadening its spectrum of action.

Therapeutic Class

Xinarox 500mg Tablet belongs to the therapeutic class of second-generation cephalosporins, known for their broad-spectrum antibacterial activity and resistance to beta-lactamase enzymes.

Storage Conditions

Store Xinarox 500mg Tablet in a cool, dry place below 30°C, away from light and moisture. Keep it out of reach of children to prevent accidental ingestion.

3 FAQ

Q1: Can I take Xinarox 500mg Tablet if I am allergic to penicillin? A1: Generally, Xinarox 500mg Tablet can be taken safely by patients with penicillin allergies, but consult your doctor as cross-reactions may occur.

Q2: What should I do if I miss a dose of Xinarox 500mg Tablet? A2: Take the missed dose as soon as you remember. If it's close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q3: Can I drink alcohol while taking Xinarox 500mg Tablet? A3: It's best to avoid alcohol while taking Xinarox 500mg as it can increase drowsiness and affect your recovery.

Disclaimer

The information provided is for informational purposes only and not a substitute for professional medical advice. Always consult a healthcare provider for medical conditions and treatment.

Keywords: Cefuroxime Axetil, Xinarox 500, bacterial infections, cephalosporin, antibiotics, Nipro JMI Pharma, pharyngitis, tonsillitis, otitis media, sinusitis, bronchitis, urinary tract infections, skin infections, gonorrhea, Lyme disease, pneumonia, bone infections, drug interactions, side effects.