Generic

Xiclav 250 combines Cefuroxime Axetil 250 mg with Clavulanic Acid 62.5 mg, developed by Ziska Pharmaceuticals Limited. This prescription medication targets bacterial infections with an effective combination of a cephalosporin antibiotic and beta-lactamase inhibitor.

Description

Xiclav 250 is a second-generation cephalosporin antibiotic with broad-spectrum antibacterial properties. It treats infections caused by various bacteria, including those resistant to typical antibiotics due to the inclusion of clavulanic acid, which enhances cefuroxime's effectiveness.

Benefits

Xiclav 250’s dual-action formula helps combat infections more efficiently, especially in bacteria producing beta-lactamase. It provides a strong defense against common respiratory, skin, urinary tract, and other infections, helping reduce resistance and promoting faster recovery.

Ingredients

• Cefuroxime Axetil: 250 mg
• Clavulanic Acid: 62.5 mg

Uses and Doses

Xiclav 250 is prescribed for bacterial infections including pharyngitis, tonsillitis, sinusitis, bronchitis, urinary tract infections, and skin infections. Dosage varies based on infection type and patient age, with adults generally taking 250–500 mg twice daily and pediatric patients requiring weight-based dosing.

Side Effects

Common side effects include nausea, vomiting, diarrhea, abdominal discomfort, and possible skin rashes. Rare but serious reactions include anaphylaxis and angioedema. Consult a doctor if any severe side effects occur.

How to Use

Take Xiclav 250 as prescribed, ideally at the same time each day. It can be taken with or without food, but taking it with meals may reduce stomach upset. Complete the entire course to prevent infection recurrence.

Pregnancy & Lactation

Though generally avoided during the first trimester, Xiclav 250 can be used later in pregnancy to treat infections. Limited quantities may pass into breast milk, so nursing mothers should use it cautiously.

Precautions and Warnings

Patients with a history of colitis or those taking diuretics should exercise caution. Discontinue use and seek immediate medical help if experiencing allergic symptoms such as rash or breathing difficulties.

Safety Information

Avoid abrupt discontinuation; inform your doctor of any other medications being taken to avoid interactions. Alcohol may intensify side effects, so limit intake during treatment.

Indications

Xiclav 250 is indicated for infections such as pharyngitis, tonsillitis, bronchitis, sinusitis, skin infections, urinary tract infections, and Lyme disease.

Pharmacology

The cephalosporin antibiotic Cefuroxime inhibits bacterial cell wall synthesis, causing cell death, while clavulanic acid neutralizes beta-lactamase, enhancing antibiotic efficacy.

Therapeutic Class

Second-generation cephalosporins.

Storage Conditions

Store below 30°C in a cool, dry place, away from light and moisture. Keep out of children's reach.

FAQ

1. Can I take Xiclav 250 with food? Yes, it may be taken with or without food.
2. What should I do if I miss a dose? Take it as soon as you remember, but don’t double the dose.
3. Is it safe during pregnancy? Use cautiously, especially in the first trimester. Consult your doctor.

Disclaimer

This information does not substitute professional medical advice. Consult your healthcare provider for personalized guidance on this medication.

Keywords: Cefuroxime, Clavulanic Acid, Xiclav 250, Ziska Pharmaceuticals, bacterial infection, antibiotic, cephalosporin, beta-lactamase inhibitor, respiratory infection, urinary infection, skin infection, bronchitis, sinusitis, pharyngitis, tonsillitis, drug interactions, antibiotic resistance, pregnancy caution, pediatric dosage, lyme disease, side effects.