Generic: Terbinafine Hydrochloride 250mg

Description: Xfin 250mg, containing Terbinafine Hydrochloride, is an antifungal medication used to treat a variety of fungal infections. It is manufactured by Square Pharmaceuticals Limited. Xfin tablets are particularly effective against infections of the toenails and fingernails, caused by dermatophytes. The tablet form of Terbinafine is primarily prescribed for systemic treatment of fungal infections due to its potent antifungal properties.

Benefits: Xfin 250mg provides a comprehensive solution for combating fungal infections. It effectively treats onychomycosis, a fungal infection of the nails, and various skin infections like tinea pedis (athlete’s foot), tinea cruris (jock itch), and tinea corporis (ringworm). The medication works by targeting the fungal cell membrane, leading to the death of the fungus and relief from symptoms.

Ingredients: The active ingredient in Xfin 250mg is Terbinafine Hydrochloride. This compound is an allylamine antifungal agent that inhibits the enzyme squalene epoxidase, crucial for the synthesis of ergosterol in fungal cell membranes. The inactive ingredients may include various fillers, binders, and preservatives that support the stability and efficacy of the tablet.

Uses and Doses: Xfin 250mg is used to treat:

• Fingernail onychomycosis: 250 mg once daily for 6 weeks.
• Toenail onychomycosis: 250 mg once daily for 12 weeks.
• Tinea infections: 250 mg daily for 2-6 weeks depending on the specific type and severity of the infection.
• For pediatric use, the dose is adjusted based on body weight and is typically administered for 6 weeks.

Side Effects: Common side effects include gastrointestinal symptoms (like diarrhea and dyspepsia), rashes, taste disturbances, and liver enzyme abnormalities. Serious but rare side effects may include liver failure, severe skin reactions, and allergic responses. Most side effects are mild and resolve upon discontinuation of the medication.

How to Use: Xfin 250mg should be taken as directed by a healthcare provider. For oral administration, it can be taken with or without food. Consistent daily intake at the same time enhances effectiveness. For the cream form, apply a thin layer to the affected area and surrounding skin, ensuring the area is clean and dry before application.

Pregnancy & Lactation: Terbinafine should be used with caution during pregnancy and lactation. There is limited clinical data on its safety in pregnant women. It is known to be secreted in breast milk, so breastfeeding mothers are advised against its use unless the benefits outweigh the potential risks.

Precautions and Warnings: Patients with liver or kidney impairment should exercise caution when using Xfin 250mg, as there is a risk of liver failure. Liver function tests are recommended before starting treatment. The medication should be discontinued if any signs of liver damage appear. It should not be used by individuals with a known hypersensitivity to Terbinafine.

Safety Information: Store Xfin 250mg in a cool, dry place away from direct light and moisture. Keep out of reach of children. The medication should not be used past its expiration date, and any unused tablets should be disposed of properly.

Indications: Xfin 250mg is indicated for the treatment of:

• Onychomycosis (fungal infections of the nail)
• Tinea pedis (athlete’s foot)
• Tinea cruris (jock itch)
• Tinea corporis (ringworm)
• Dermatophytosis and other fungal infections are caused by specific microorganisms.

Pharmacology: Terbinafine acts by inhibiting the enzyme squalene epoxidase, leading to ergosterol deficiency in fungal cell membranes and the accumulation of squalene. This disruption causes cell death. It is effective against a wide range of fungi, including Trichophyton, Microsporum, and Epidermophyton species.

Therapeutic Class: Xfin 250mg belongs to the class of drugs used for treating subcutaneous and systemic mycoses, specifically classified under Topical Antifungal preparations.

Storage Conditions: Store below 25°C in a cool, dry place protected from light and moisture. Keep the medicine out of reach of children.

FAQ:

1. How long does it take for Xfin 250mg to show results? Results can vary, but noticeable improvement in nail infections may take several weeks to months after starting treatment, as new, healthy nail growth replaces the infected areas.
2. Can I use Xfin 250mg if I have liver problems? Patients with liver impairment should avoid using Xfin 250mg due to the risk of severe liver damage. Consult with a healthcare provider for alternative treatments.
3. What should I do if I miss a dose? Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up to make up for a missed dose.

Disclaimer: The provided information is for educational purposes and is not a substitute for professional medical advice. Consult a healthcare provider for personalized guidance regarding any medical condition or treatment.

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