Generic
Tranexamic Acid

Description
Tranexamic Acid is an antifibrinolytic medication used to prevent excessive bleeding. It works by inhibiting the activation of plasminogen, preventing the breakdown of fibrin clots. It is primarily used in situations where there is increased fibrinolysis, such as surgery, trauma, or conditions like menorrhagia and hereditary angioedema.

Benefits
Tranexamic Acid helps in controlling excessive bleeding in various medical conditions such as surgery, menorrhagia, and dental procedures. It reduces blood loss and the need for transfusions, offering targeted hemostatic support in fibrinolysis-related conditions.

Ingredients
Active Ingredient: Tranexamic Acid.

Uses and Doses
Tranexamic Acid is used for hemorrhage in patients with fibrinolytic disorders, including surgeries, menorrhagia, epistaxis, and gastrointestinal bleeding. The dosage depends on the indication, ranging from 1-1.5g orally or via intravenous injection, taken 2-3 times daily. Doses should be adjusted based on the patient's renal function and specific clinical conditions.

Side Effects
Common side effects include gastrointestinal discomfort, which is usually mild and transient. Allergic skin reactions may also occur. Rapid intravenous injections can cause hypotension.

How to Use
Orally, Tranexamic Acid should be taken with or after food to minimize gastrointestinal discomfort. For intravenous use, it must be injected slowly at a rate of 1 ml per minute to avoid hypotension.

Pregnancy & Lactation
Tranexamic Acid crosses the placenta, so its use during pregnancy should be limited and under medical supervision. It is excreted into breast milk, but at therapeutic doses, it is unlikely to affect the infant.

Precautions and Warnings
Patients with a history of thromboembolic events or irregular menstrual bleeding should use Tranexamic Acid cautiously under medical supervision. Regular eye examinations are advised during long-term use, as color vision disturbances may occur.

Safety Information
Tranexamic Acid should be used with caution in patients with renal impairment and those at high risk of thrombosis. Elderly patients may require lower doses due to potential decreased organ function.

Indications
Tranexamic Acid is indicated for controlling hemorrhage in conditions associated with increased fibrinolysis, such as menorrhagia, surgeries (prostatectomy, dental), epistaxis, gastrointestinal bleeding, and hereditary angioedema.

Pharmacology
Tranexamic Acid inhibits plasminogen activation, reducing fibrin clot breakdown. It is rapidly absorbed, and about 40-45% of the dose is excreted in the urine within 24 hours.

Therapeutic Class
Anti-fibrinolytic drugs, Haemostatic drugs.

Storage Conditions
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.

FAQ

1. What is Tranexamic Acid used for?
   Tranexamic Acid is used to prevent or treat excessive bleeding in conditions like surgery, menorrhagia, and hereditary angioedema.
2. Can I take Tranexamic Acid if I am pregnant?
   It should only be used during pregnancy under strict medical supervision, as it crosses the placenta.
3. How should I take Tranexamic Acid?
   It can be taken orally or via intravenous injection, with doses tailored based on the patient's condition and renal function.

Disclaimer
This content is for informational purposes only and does not replace professional medical advice. Always consult a healthcare provider for appropriate diagnosis and treatment.

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