Generic

Sacubitril + Valsartan
Vivanta 24/26 is a combination medication containing Sacubitril, a neprilysin inhibitor, and Valsartan, an angiotensin receptor blocker (ARB).

Description

Vivanta 24/26 is used to manage chronic heart failure by reducing cardiovascular death and hospitalizations. It is suitable for both adults and children aged one year or older with specific heart failure conditions.

Benefits

• Reduces hospitalization due to heart failure.
• Decreases risk of cardiovascular mortality.
• Improves heart efficiency by relaxing blood vessels.
• Helps control symptoms of heart failure in pediatric and adult patients.

Ingredients

Active: Sacubitril (24 mg) + Valsartan (26 mg).

Uses and Doses

Vivanta 24/26 is used for chronic heart failure (NYHA Class II-IV). Starting dose: 24/26 mg twice daily for certain patients. Maintenance dose: 97/103 mg twice daily as tolerated. Pediatric doses are weight-specific.

Side Effects

Common side effects include dizziness, hypotension, cough, hyperkalemia, and renal impairment. Rare effects include angioedema and severe hypotension.

How to Use

Take Vivanta 24/26 as directed by a healthcare provider. Swallow whole with water, with or without food, at the same time each day. Avoid abrupt discontinuation.

Pregnancy & Lactation

Not recommended during pregnancy due to potential fetal harm. Avoid during lactation. Consult a healthcare provider for guidance.

Precautions and Warnings

Monitor for angioedema, hyperkalemia, and renal function decline. Not recommended with ACE inhibitors or certain diabetic medications like aliskiren. Avoid potassium-rich diets or supplements.

Safety Information

• Contraindicated in patients with hypersensitivity to ingredients.
• Ensure a gap of 36 hours when switching from an ACE inhibitor to Vivanta.
• Regular monitoring of blood pressure and potassium levels is necessary.

Indications

Vivanta 24/26 is indicated for heart failure management in adults and children, particularly those with reduced ejection fraction.

Pharmacology

The medication inhibits neprilysin via Sacubitril's active metabolite and blocks angiotensin II effects through Valsartan. This combination improves cardiovascular and renal outcomes.

Therapeutic Class

Angiotensin receptor-neprilysin inhibitor (ARNI).

Storage Conditions

Store below 30°C, in a dry place protected from moisture. Keep out of reach of children.

3 FAQ

1. Can Vivanta 24/26 be taken with food?
   Yes, it can be taken with or without food.
2. What is the target dose for adults?
   The target maintenance dose is 97/103 mg twice daily.
3. Can children take Vivanta 24/26?
   Yes, for children aged one year or older, with weight-specific dosing.Keywords: heart failure medication, sacubitril valsartan, Vivanta 24/26, Beximco Pharmaceuticals, angiotensin receptor blocker, ARNI, heart failure treatment, neprilysin inhibitor, chronic heart failure, pediatric heart failure, cardiovascular health, valsartan combination, hypertension therapy, heart ejection fraction, kidney monitoring, hypotension risk, hyperkalemia management, ACEi alternative, NYHA class II-IV, cardiology medication.