Generic

Tofacitinib 5mg

Description

Tofatin 5, containing Tofacitinib 5mg, is a treatment for moderate to severe rheumatoid arthritis. Manufactured by Ziska Pharmaceuticals Limited, it is designed to reduce joint inflammation and slow disease progression. Tofacitinib, a Janus kinase (JAK) inhibitor, works by blocking enzymes that contribute to inflammation, offering relief for patients who have not responded adequately to methotrexate or other treatments.

Benefits

Tofatin 5 reduces inflammation, alleviates pain, and helps slow the damage to joints caused by rheumatoid arthritis. It can be used as monotherapy or in combination with other medications, offering flexibility in treatment. It also provides rapid symptom relief for patients who are intolerant to or have had an inadequate response to methotrexate.

Ingredients

Active Ingredient: Tofacitinib 5mg
Inactive Ingredients: Excipients as per formulation.

Uses and Doses

Tofatin 5 is used for treating moderate to severe rheumatoid arthritis in adults. The recommended dose is 5 mg taken twice daily, with or without food. It can be taken as a standalone therapy or in combination with methotrexate or other DMARDs. Always follow your physician's dosage recommendations.

Side Effects

Common side effects include diarrhea, upper respiratory infections, headache, nasopharyngitis, and hypertension. Serious but less frequent side effects include blood clots and tears in the stomach or intestines. Consult your doctor if you experience any unusual symptoms.

How to Use

Take Tofatin 5 in the dose prescribed by your doctor. Swallow the tablet whole with water; do not crush or chew it. It can be taken with or without food. Consistency in timing will aid in effectiveness. Do not discontinue use without consulting your doctor.

Pregnancy & Lactation

Tofatin 5 is classified as Pregnancy Category C. There are no adequate studies in pregnant women, so it should only be used if the benefits outweigh the risks. It is unknown whether the drug passes into breast milk, so breastfeeding is not recommended during treatment.

Precautions and Warnings

Do not take Tofatin 5 if you have an active infection. It can suppress your immune system, increasing the risk of infections. Patients with latent tuberculosis should undergo antimycobacterial treatment before using Tofatin 5. Regular blood tests may be required to monitor liver, kidney, and blood cell functions.

Safety Information

Tofatin 5 can increase the risk of infections and blood clots. Patients should avoid live vaccines while on this medication. It is not recommended for children under 18 or those with severe liver or kidney impairment. Always inform your doctor of your medical history before starting the treatment.

Indications

Tofatin 5 is indicated for the treatment of moderate to severe rheumatoid arthritis in adults who have not responded adequately to methotrexate or other DMARDs.

Pharmacology

Tofacitinib, the active ingredient in Tofatin 5, is a Janus kinase (JAK) inhibitor. It blocks the signaling pathway that contributes to the immune response and inflammation in rheumatoid arthritis, reducing the production of pro-inflammatory cytokines.

Therapeutic Class

Immunosuppressant

Storage Conditions

Store Tofatin 5 below 25°C in a dry place. Keep it out of reach of children and protect it from moisture.

FAQ

1. Can I take Tofatin 5 if I am pregnant?
Tofatin 5 should only be taken during pregnancy if necessary and under a doctor's supervision.

2. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double up.

3. How long does it take for Tofatin 5 to work?
It may take 3 to 6 months to feel the maximum effects of Tofatin 5. Continue using it as prescribed by your doctor.

Disclaimer

The information provided here is for general purposes and should not replace the advice of a healthcare provider. Always consult your physician before starting any medication.

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