Generic

Acarbose

Description

Sugatrol 50 is an oral alpha-glucosidase inhibitor for managing Type 2 diabetes mellitus. It works by slowing down the digestion of carbohydrates in the intestine, which helps control blood sugar levels after meals. Unlike other diabetes medications, Sugatrol 50 does not stimulate insulin secretion, making it effective in preventing postprandial hyperglycemia without causing hypoglycemia when used alone.

Benefits

Sugatrol 50 helps individuals with Type 2 diabetes manage their blood sugar levels, especially after meals. It reduces post-meal glucose spikes by slowing down carbohydrate breakdown and absorption. When combined with sulfonylureas, metformin, or insulin, it provides better glycemic control while minimizing weight gain associated with some diabetes medications.

Ingredients

Each Sugatrol 50 tablet contains 50 mg of acarbose, a potent alpha-glucosidase inhibitor that delays the intestines' carbohydrate digestion and glucose absorption.

Uses and Doses

Sugatrol 50 is prescribed as an adjunct to diet and exercise in individuals with Type 2 diabetes mellitus.

• Adults (Starting Dose):
  • 25 mg three times daily with meals.
  • Gradual dose adjustment may be necessary to minimize gastrointestinal side effects.
• Maintenance Dose:
  • 50 mg three times daily (t.i.d).
  • Some patients may benefit from an increased dose of 100 mg t.i.d based on glycemic response.
• Dose Adjustment:
  • The dosage should be adjusted every 4 to 8 weeks, depending on blood glucose levels and tolerability.
  • Maximum recommended dose: 100 mg t.i.d.

Side Effects

Common side effects include flatulence, diarrhoea, stomach discomfort, constipation, and bloating. These temporary symptoms typically improve over time as the body adjusts to the medication. Severe side effects, though rare, include liver enzyme elevation, allergic reactions, and hypoglycemia when combined with other diabetes medications.

How to Use

To ensure optimal effectiveness, takeSugatrol 50 at the start of each main meal. The tablet should be swallowed whole with a glass of water. Do not crush or chew the tablet. Follow the prescribed dietary guidelines to minimize gastrointestinal side effects.

Pregnancy & Lactation

• Pregnancy: Sugatrol 50 is classified as Pregnancy Category B. The safety of Acarbose in pregnant women is not well established, and it should be used only if needed.
• Lactation: Small amounts of Acarbose metabolites have been found in the milk of lactating animals. Due to the lack of data on human lactation, breastfeeding mothers should avoid this medication or consult a physician.

Precautions and Warnings

Sugatrol 50 should be used cautiously in individuals with intestinal disorders, liver disease, or those at risk of hypoglycemia. Since it delays carbohydrate digestion, hypoglycemia caused by sulfonylureas or insulin should be treated with glucose (dextrose) instead of sucrose. Patients should undergo regular liver function tests during prolonged use.

Safety Information

Sugatrol 50 is not recommended for individuals with:

• Hypersensitivity to Acarbose or its components.
• Diabetic ketoacidosis or cirrhosis.
• Inflammatory bowel disease (IBD), colonic ulcers, or intestinal obstruction.
• Chronic intestinal diseases that impair digestion or absorption.

Indications

Sugatrol 50 is indicated for:

• Type 2 diabetes mellitus management, particularly postprandial blood glucose control.
• Adjunct therapy with sulfonylureas, metformin, or insulin to improve glycemic regulation.

Pharmacology

Acarbose works by competitively inhibiting pancreatic alpha-amylase and intestinal alpha-glucosidase enzymes, delaying the breakdown of complex carbohydrates into glucose. This reduces post-meal blood sugar spikes, making it a valuable addition to diabetes treatment plans.

Therapeutic Class

Alpha-Glucosidase Inhibitors (Oral Antidiabetics).

Storage Conditions

Store below 25°C, away from moisture and direct sunlight. Keep out of reach of children.

3 FAQ

Q1: Can Sugatrol 50 be taken alone for diabetes management?
Sugatrol 50 can be used alone or with other diabetes medications such as metformin, sulfonylureas, or insulin.

Q2: Does Sugatrol 50 cause weight gain?
No, Acarbose does not promote weight gain and may even help counteract weight gain caused by other diabetes medications.

Q3: What should I do if I miss a dose?
Take Sugatrol 50 with the next meal. Do not double the dose to make up for the missed one.

Disclaimer

This content is for informational purposes only and should not be considered medical advice. Always consult a healthcare professional before starting or adjusting any medication.

 

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