Generic

Rivaroxaban

Description

Roxolyte is an anticoagulant medication from Renata Pharma Ltd containing Rivaroxaban 10mg. It prevents blood clots by inhibiting Factor Xa. It is used to lower the risk of stroke and systemic embolism in various conditions, such as nonvalvular atrial fibrillation, deep vein thrombosis (DVT), and pulmonary embolism (PE).

Benefits

• Prevents stroke and embolism in nonvalvular atrial fibrillation.
• Reduces risk of DVT and PE recurrence.
• Effective for post-surgery clot prevention in hip and knee replacements.
• No routine blood monitoring is required compared to traditional anticoagulants.

Ingredients

Active Ingredient: Rivaroxaban 10mg
Other Ingredients: Pharmaceutical-grade excipients.

Uses and Doses

Nonvalvular Atrial Fibrillation:
20 mg once daily (Creatinine clearance >50 mL/min), 15 mg once daily (Creatinine clearance 15-50 mL/min), taken with meals.

DVT & PE Treatment:
15 mg twice daily for 21 days, followed by 20 mg daily, with food.

Post-Surgical Prophylaxis:
10 mg daily for 12 days (knee) or 35 days (hip), with or without food.

Side Effects

Common side effects include bleeding, dizziness, nausea, headache, and fatigue. Severe reactions like jaundice, severe bleeding, or Stevens-Johnson syndrome are rare.

How to Use

Take Roxolyte orally with or without food as prescribed. For higher doses (15-20 mg), consume with meals. Maintain a consistent schedule for optimal results.

Pregnancy & Lactation

Roxolyte is classified as a Category C drug. Its safety during pregnancy and lactation is not established. Consult a doctor before use.

Precautions and Warnings

Discontinuation without alternative anticoagulation increases thrombotic risks. Avoid in patients with active bleeding, severe liver disease, or renal impairment. Use cautiously with NSAIDs, antiplatelet drugs, or when undergoing surgery.

Safety Information

• Avoid sudden discontinuation.
• Inform the doctor about all concurrent medications.
• Avoid hazardous activities if dizziness occurs.

Indications

• Nonvalvular atrial fibrillation.
• Treatment and prevention of DVT and PE.
• Prophylaxis for clot formation post-hip and knee replacement.

Pharmacology

Rivaroxaban selectively inhibits Factor Xa, interrupting the coagulation cascade, thereby reducing thrombin production and preventing clot formation.

Therapeutic Class

Oral anticoagulants

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of children’s reach.

3 FAQ

1. What is Roxolyte used for?
   Roxolyte is used to prevent stroke, systemic embolism, DVT, and PE.
2. Can Roxolyte cause bleeding?
   Yes, bleeding is a common side effect. Notify a doctor if it occurs.
3. Can pregnant women take Roxolyte?
   Consult a doctor before use during pregnancy or lactation.

Disclaimer

This information is provided for general knowledge and should not replace medical advice. Always consult a healthcare provider for personalized guidance.

Keywords: Rivaroxaban, Roxolyte 10mg, anticoagulant, blood thinner, stroke prevention, DVT treatment, PE prevention, atrial fibrillation, Renata Pharma, oral anticoagulants, Factor Xa inhibitor, blood clot prevention, nonvalvular AF, knee surgery, hip surgery, clot management, thrombotic events, prescription medication, side effects, dosage instructions