Generic

Rosuvastatin 5 mg.

Description

Rolip 5 is a tablet manufactured by Renata Pharma Ltd., containing 5 mg of Rosuvastatin. Rosuvastatin is used to manage cholesterol levels, specifically to treat hypercholesterolemia and dyslipidemia. This medication works by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in cholesterol synthesis, and enhancing LDL receptors for better cholesterol breakdown.

Benefits

Rolip 5 helps lower high cholesterol levels, reduces the risk of heart disease, and improves lipid profile in patients with both familial and non-familial hypercholesterolemia. It also aids in the primary prevention of cardiovascular diseases.

Ingredients

Active ingredient: Rosuvastatin 5 mg.

Uses and Doses

Rolip 5 is used to treat hypercholesterolemia, both heterozygous familial and non-familial, homozygous familial hypercholesterolemia, mixed dyslipidemia, and to prevent primary cardiovascular diseases. The typical dosage range is 5-40 mg once daily, with adjustments based on individual patient response and condition.

Side Effects

Common side effects include headaches, muscle pain, constipation, abdominal pain, nausea, and weakness. Although rare, muscle issues like myopathy and rhabdomyolysis may occur.

How to Use

Take the tablet once daily, preferably at the same time each day, with or without food. Follow your doctor’s instructions regarding dosage adjustments based on your cholesterol levels.

Pregnancy & Lactation

Rosuvastatin is contraindicated during pregnancy and breastfeeding. The safety of this medication in pregnant women has not been established, and it is unknown if it is excreted in human milk.

Precautions and Warnings

Patients over 65 years, those with hypothyroidism, renal impairment, or taking certain medications (e.g., cyclosporine, fibrates) should be cautious when using Rosuvastatin. Liver enzyme monitoring is recommended due to the risk of liver abnormalities. Patients should report any unexplained muscle pain or weakness.

Safety Information

Do not take if you have a known allergy to Rosuvastatin or if you are pregnant or breastfeeding. Regular liver enzyme tests may be necessary to ensure safety during long-term use.

Indications

Rolip 5 is indicated for the treatment of hypercholesterolemia, including familial and non-familial, mixed dyslipidemia, and the primary prevention of cardiovascular diseases.

Pharmacology

Rosuvastatin is an HMG-CoA reductase inhibitor that works by increasing the hepatic LDL receptor count, improving LDL uptake and catabolism. It also reduces the synthesis of VLDL, thereby decreasing total VLDL and LDL particles.

Therapeutic Class

Statins and other anti-anginal and anti-ischemic drugs.

Storage Conditions

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

3 FAQ

1. Can I take Rolip 5 without food?
   Yes, Rolip 5 can be taken with or without food.
2. What should I do if I miss a dose?
   Take the missed dose as soon as you remember, but skip it if it’s almost time for your next dose.
3. Can I drink alcohol while on Rosuvastatin?
   Limit alcohol intake as it may increase the risk of liver complications.

Disclaimer

This information is not intended as medical advice. Consult your healthcare provider for personalized guidance and recommendations regarding the use of Rosuvastatin or any other medication.

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