Generic Sulfasalazine

Description: Reumazin is a tablet formulation containing 500mg of Sulfasalazine manufactured by Aristopharma Ltd. It is primarily used for treating rheumatoid arthritis, juvenile arthritis, Crohn’s disease, and ulcerative colitis by reducing inflammation and modulating the immune system.

Benefits: Reumazin helps manage inflammatory conditions by reducing symptoms such as joint pain, swelling, and gastrointestinal discomfort. It is effective in treating rheumatoid arthritis, ulcerative colitis, and Crohn’s disease, particularly in patients who do not respond well to NSAIDs.

Ingredients Each tablet of Reumazin contains 500mg of Sulfasalazine as the active ingredient, which works as an anti-inflammatory and immunomodulatory agent.

Uses and Doses Reumazin treats rheumatoid arthritis, juvenile arthritis, Crohn’s disease, and ulcerative colitis. The dosage is adjusted based on patient tolerance and condition severity.

For adults with Crohn’s disease, the recommended dose is 500mg taken orally 2 to 4 times daily with food. The initial dose for ulcerative colitis in children (6 years and older) is 40 to 60 mg/kg/day divided into 3 to 6 doses. In rheumatoid arthritis, the recommended adult dose is 2g daily in divided doses, starting with a lower dose to minimize gastrointestinal intolerance. Pediatric patients (6 years and older) with juvenile rheumatoid arthritis require an initial dose of 10 mg/kg/day in two divided doses, with a maximum of 2g per day.

Side Effects Common side effects include nausea, vomiting, headache, gastric distress, abdominal pain, loss of appetite, dyspepsia, and temporary infertility in men. In rare cases, it may cause disorientation or allergic reactions.

How to Use Reumazin should be taken orally with food and plenty of water to reduce stomach irritation. The dosage should be followed exactly as the physician prescribes to ensure effectiveness and minimize side effects.

Pregnancy & Lactation Reumazin is categorized as Pregnancy Category B, meaning it should only be used during pregnancy if necessary. Caution is advised while breastfeeding, as the drug may pass into breast milk.

Precautions and Warnings Patients with liver or kidney impairment, G6PD deficiency, or allergic bronchial asthma should use Reumazin cautiously. During prolonged use, liver and kidney function must be monitored. Patients should also inform their doctors of any history of hypersensitivity to sulfonamides or salicylates.

Patients with intestinal or urinary obstruction should not use Safety Information Reumazin. It should be stored safely out of children’s reach. Regular medical check-ups are necessary to monitor any adverse effects.

Indications Reumazin is indicated for the treatment of rheumatoid arthritis, juvenile arthritis, Crohn’s disease, and ulcerative colitis. It is beneficial for patients who do not respond well to NSAIDs.

Pharmacology Sulfasalazine has anti-inflammatory and immunomodulatory properties. While its exact mode of action is unknown, it is thought to work by inhibiting inflammatory pathways and reducing immune system overactivity. It accumulates in connective tissue, serous fluids, the liver, and the intestinal wall, helping relieve symptoms of inflammatory diseases.

Therapeutic Class Drugs for Irritable Bowel Syndrome, Drugs used for Rheumatoid Arthritis, Ulcerative Colitis.

Storage Conditions: Store in a cool, dry place, away from light and moisture, at room temperature.

3 FAQ

1. Can I take Reumazin with other medications?
   • Please consult your doctor before taking Reumazin with other medications, as it may interact with folic acid and digoxin.
2. How long does it take for Reumazin to work?
   • It may take a few weeks to notice symptom improvement. Continue taking the medication as directed by your doctor.
3. Can Reumazin be stopped abruptly?
   • Do not stop taking Reumazin suddenly. Consult your doctor for a proper discontinuation plan to avoid symptom flare-ups.

Disclaimer: This content is for informational purposes only and should not replace medical advice from a healthcare professional. Always consult your doctor before starting any medication.

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