Generic Cefixime Trihydrate

Description: Orcef 200 is an orally active cephalosporin antibiotic manufactured by Renata Pharma Ltd. It exhibits marked bactericidal activity against various Gram-positive and Gram-negative organisms, effectively treating acute bacterial infections. It works by inhibiting bacterial cell wall synthesis, thus killing the bacteria.

Benefits Orcef 200 is effective against antibiotic-resistant infections, including upper and lower respiratory tract infections, urinary tract infections, and typhoid fever. It is stable in the presence of beta-lactamase enzymes, allowing it to target resistant pathogens effectively.

Ingredients The active ingredient in Orcef 200 is Cefixime Trihydrate, a third-generation cephalosporin antibiotic.

Uses and Doses Orcef 200 treats bacterial infections such as urinary tract infections, bronchitis, pharyngitis, tonsillitis, and otitis media. The typical dose for adults and children over 10 is 200-400 mg daily, either as a single dose or in two divided doses. Children under 10 years old are dosed at 8 mg/kg/day. Dosage adjustments may be necessary for patients with renal impairment.

Side Effects Common side effects include diarrhea, nausea, abdominal pain, dizziness, and hypersensitivity reactions such as rash or pruritus. Rare side effects include pseudomembranous colitis, thrombocytopenia, and mild changes in liver and renal function tests.

How to Use Orcef 200 can be taken with or without food. Even if symptoms improve, completing the entire treatment course before finishing the prescribed dosage is essential.

Pregnancy & Lactation The safety of Orcef 200 during pregnancy has not been established. It should only be used if a physician deems it essential. It is unknown if Cefixime is excreted in human milk, so caution is advised for nursing mothers.

Precautions and Warnings Due to its cross-allergenicity, Orcef 200 should be administered cautiously in patients allergic to penicillins or cephalosporins. It should also be used cautiously in patients with severe renal impairment. Antibiotic use can alter gut flora and may lead to an overgrowth of Clostridium difficile, potentially causing diarrhea.

Safety Information: Keep Orcef 200 out of reach of children. Avoid alcohol consumption during treatment. Report any severe allergic reactions or persistent side effects to a healthcare professional immediately.

Indications Orcef 200 is indicated for infections caused by susceptible organisms, including upper and lower respiratory tract infections, urinary tract infections, and typhoid fever.

Pharmacology Cefixime, the active component of Orcef 200, is a semisynthetic cephalosporin with broad-spectrum bactericidal activity. It disrupts bacterial cell wall synthesis and is resistant to beta-lactamase enzymes.

Therapeutic Class Third-generation Cephalosporins

Storage Conditions Store below 30ºC in a dry place, away from light and moisture. Keep out of the reach of children.

3 FAQ

1. What is Orcef 200 used for? It treats bacterial infections like bronchitis, urinary tract infections, and typhoid fever.
2. Does Orcef 200 work for viral infections? No, it is ineffective against viral infections like colds or the flu.
3. What should I do if I miss a dose? Take the missed dose as soon as you remember unless it is close to the next dose. Do not double up.

Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Consult a doctor for personalized guidance.

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