Generic

Cefixime Trihydrate is the generic name of Orcef 200, a third-generation cephalosporin antibiotic.

Description

Orcef 200 is a semisynthetic, broad-spectrum cephalosporin antibiotic produced by Renata Pharmaceuticals Ltd. It is formulated with Cefixime Trihydrate 200mg and is primarily used for treating bacterial infections. Cefixime works by inhibiting the formation of bacterial cell walls, making it effective against various gram-positive and gram-negative bacteria.

Benefits

Orcef 200 offers effective treatment against infections like urinary tract infections, otitis media, pharyngitis, bronchitis, and uncomplicated gonorrhea. Its broad-spectrum nature and stability against beta-lactamase enzymes make it useful in treating penicillin-resistant bacteria.

Ingredients

The key active ingredient in Orcef 200 is Cefixime Trihydrate 200mg. Inactive components vary based on formulation.

Uses and Doses

Orcef 200 is typically prescribed for 7 to 14 days, depending on the severity of the infection. For adults and children over 12, the recommended dosage is 200-400 mg daily, either as a single dose or divided into two doses. For gonococcal infections, a single oral dose of 400 mg is suggested. Dosage for children varies by age and weight.

Side Effects

Common side effects include diarrhea, stool alterations, nausea, abdominal pain, vomiting, headache, and dizziness. Allergic reactions such as rash, pruritus, and urticaria may also occur.

How to Use

Orcef 200 should be taken as directed by your physician, with or without food. It’s crucial to complete the entire course, even if symptoms improve, to avoid bacterial resistance.

Pregnancy & Lactation

The safety of Cefixime during pregnancy has not been fully established. Use is recommended only if necessary, under the advice of a physician. The excretion of Cefixime in human milk is not confirmed, so breastfeeding mothers should proceed with caution.

Precautions and Warnings

Use caution in patients with a history of gastrointestinal issues or severe renal impairment. Dosage adjustments are necessary for patients with creatinine clearance below 20 ml/min. Orcef 200 should not exceed a daily dose of 200 mg in such cases.

Safety Information

Orcef 200 requires a prescription and should be used with caution in individuals with a history of allergies to cephalosporins or penicillin.

Indications

Orcef 200 is indicated for the treatment of infections caused by bacteria such as Escherichia coli, Proteus mirabilis, Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria gonorrhoeae.

Pharmacology

Cefixime, the active ingredient in Orcef 200, works by interfering with bacterial cell wall production, making it bactericidal. It remains stable in the presence of beta-lactamase, allowing it to treat infections resistant to penicillins and some cephalosporins.

Therapeutic Class

Orcef 200 belongs to the Third-Generation Cephalosporin class of antibiotics.

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.

FAQ

1. Can Orcef 200 be taken on an empty stomach? Yes, it can be taken with or without food.
2. What should I do if I miss a dose? Take it as soon as you remember, but skip it if it's close to the next dose.
3. Is Orcef 200 safe during pregnancy? Only if necessary under medical supervision.

Disclaimer

Consult a healthcare provider for personalized advice. The information provided here is for reference purposes only.

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