Generic
Esomeprazole Magnesium Trihydrate

Description
Opton 20 is a medication designed to reduce stomach acid production. It is commonly used for treating conditions like acid reflux, heartburn, peptic ulcers, and other gastrointestinal issues. Manufactured by Beximco Pharmaceuticals Ltd., Opton 20 contains Esomeprazole, which is a proton pump inhibitor that helps manage acid-related discomforts.

Benefits
Opton 20 offers significant relief from chronic heartburn, gastroesophageal reflux disease (GERD), and aids in the healing of erosive esophagitis. It is also effective in treating duodenal and gastric ulcers, managing symptoms of Zollinger-Ellison syndrome, and eradicating Helicobacter pylori when used in combination with other medications.

Ingredients
The active ingredient in Opton 20 is Esomeprazole Magnesium Trihydrate, which acts as a proton pump inhibitor to suppress stomach acid production.

Uses and Doses
Opton 20 is primarily used to treat heartburn, GERD, Zollinger-Ellison syndrome, peptic ulcers, and acid-related dyspepsia. It can also help eradicate Helicobacter pylori infection when combined with other drugs. The typical dose ranges from 20 to 40 mg per day, depending on the condition being treated. For erosive esophagitis, treatment lasts for 4-8 weeks, while maintenance therapy involves a 20 mg dose daily for up to 6 months.

Side Effects
Common side effects include headache, nausea, abdominal pain, constipation, diarrhea, and dry mouth. Rare but serious side effects may include bone fractures, hypomagnesemia, and interstitial nephritis.

How to Use
Opton 20 should be taken on an empty stomach, about one hour before meals. The tablets must be swallowed whole without crushing or chewing. Follow the prescribed dosage and duration by your doctor for optimal results.

Pregnancy & Lactation
There are no sufficient studies to confirm the safety of Opton 20 during pregnancy. Esomeprazole is present in human milk, so breastfeeding should be avoided when using this medication.

Precautions and Warnings
Patients with severe liver impairment or a history of hypersensitivity to Esomeprazole should avoid using Opton 20. Long-term use may lead to magnesium deficiencies, increasing the risk of bone fractures. Avoid using this medication without consulting your doctor if you are pregnant or breastfeeding.

Safety Information
Opton 20 is generally safe when taken as prescribed. However, prolonged use may increase the risk of infections such as pneumonia or gastrointestinal candidiasis. Regular medical reviews are recommended to monitor for any side effects.

Indications
Opton 20 is indicated for GERD, Zollinger-Ellison syndrome, Helicobacter pylori infection, peptic ulcers, erosive esophagitis, and acid-related dyspepsia.

Pharmacology
Esomeprazole, a proton pump inhibitor, works by inhibiting the H+/K+-ATPase enzyme in gastric parietal cells. This reduces gastric acid production, providing relief from acid-related symptoms.

Therapeutic Class
Proton Pump Inhibitors (PPI)

Storage Conditions
Store in a cool, dry place away from light and moisture. Keep the temperature below 30°C and out of reach of children.

FAQ

1. Can I take Opton 20 during pregnancy?
   Opton 20 is not recommended during pregnancy unless deemed necessary by a doctor. Consult your doctor for guidance.
2. How long does it take for Opton 20 to work?
   Relief from symptoms may take several days, but complete healing can take 4-8 weeks, depending on the condition.
3. What should I do if I miss a dose?
   Take the missed dose as soon as you remember, but skip it if it’s almost time for your next scheduled dose. Do not double the dose.

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