Introduction:

Omidon 10 is a prescription medication utilized in treating indigestion, nausea, and vomiting. It functions by blocking the substance in the brain responsible for triggering nausea or vomiting while also enhancing stomach movement, thereby improving digestion. Dosage and duration should be followed as advised by a doctor. It's crucial to inform the doctor about all medications being taken as interactions may occur. Common side effects include headache, dry mouth, stomach pain, and diarrhea. It can cause dizziness and sleepiness, so activities requiring mental focus should be avoided. Alcohol consumption should also be avoided as it can exacerbate sleepiness. Adequate fluid intake is recommended to prevent dehydration, especially due to the possibility of diarrhea. Before usage, individuals should inform their doctor if they have liver or kidney problems, or if they are pregnant. Omidon 10 is contraindicated in cases of bleeding ulcers of the stomach.

Uses of Omidon 10:

• Indigestion
• Nausea
• Vomiting

Side Effects of Omidon 10:

• Common:
  • Headache
  • Dry mouth
  • Stomach pain
  • Diarrhea

How to Use Omidon 10:

• Take as directed by the doctor, typically before meals.
• Swallow whole, without chewing or crushing.
• Should be taken on an empty stomach.

How Omidon 10 Works: Omidon 10 is a prokinetic medication. It acts on the brain's vomiting control region and enhances movement in the upper digestive tract, aiding in smoother food passage through the stomach.

What if You Forget to Take Omidon 10? If a dose is missed, take it as soon as remembered. However, if it's nearly time for the next dose, skip the missed one. Do not double the dose.

Quick Tips:

• Omidon 10 helps with nausea, vomiting, and indigestion.
• Take before meals as prescribed.
• Can cause dizziness and sleepiness; avoid activities requiring mental focus.
• Avoid alcohol consumption.
• Manage dry mouth with mouth rinses, good oral hygiene, increased water intake, and sugarless candy.
• Inform the doctor of persistent diarrhea, fever, or stomach pain.
• Do not exceed 7 days of usage without consulting a doctor.

Brief Description: Indication:

• Gastritis
• Lactation
• Migraine
• Nausea and vomiting
• Gastroparesis
• Non-ulcer dyspepsia

Administration:

• Should be taken on an empty stomach, 15-30 minutes before meals.

Adult Dose:

• Oral:
  • Nausea and vomiting: 10-20 mg every 4-8 hours. Max: 80 mg/day.
  • Non-ulcer dyspepsia: 10 mg 3-4 times daily. Max: 20 mg 3-4 times daily. The last dose is at bedtime.
  • Migraine: 20 mg every 4 hours. Max: 4 doses/24 hours.
• Rectal: Nausea and vomiting: 60 mg twice daily.
• Elderly and hepatic impairment: No dosage adjustment is required.

Child Dose:

• Oral: 0.2 - 0.4 mg/kg every 4 - 8 hours daily.
• Rectal: <12 years >15 kg: 30 mg twice daily; >12 years >35 kg: 60 mg twice daily.

Renal Dose:

• Mild to moderate impairment: No dosage adjustment is needed.
• Severe impairment: Reduce dosing to 1-2 times daily with prolonged treatment.

Contraindication:

• Hypersensitivity
• GI hemorrhage, obstruction, and perforation
• Patients with prolactin-releasing pituitary hormone
• Chronic administration or routine prophylaxis of postoperative nausea and vomiting

Mode of Action: Domperidone, the active ingredient, is a peripheral dopamine-receptor blocker. It enhances gastrointestinal coordination, lowers esophageal sphincter pressure, and facilitates gastric emptying and small bowel transit time.

Precaution:

• Phaeochromocytoma
• Children under 2 years, elderly
• Renal or hepatic impairment
• Pregnancy and lactation

Side Effects:

• Drowsiness
• Extrapyramidal reactions
• Galactorrhea
• Gynecomastia
• Constipation or diarrhea
• Lassitude
• Decreased libido
• Skin rash
• Itching
• Potentially Fatal: Convulsions, arrhythmias, cardiac arrest, dysrhythmias in patients with CV disease or hypokalemia, seizures, hypertensive crisis in patients with phaeochromocytoma.

Interaction:

• May antagonize the hyperprolactinemic effect of bromocriptine.
• May antagonize the prokinetic effect with opioid analgesics and antimuscarinics.
• Potentially Fatal: Potent CYP3A4 inhibitors (e.g., ketoconazole, erythromycin, ritonavir) may increase serum domperidone levels, raising the risk of QT prolongation.

Keywords: Omidon 10, prescription medication, indigestion, nausea, vomiting, stomach issues, side effects, medical caution, dosage, duration, contraindications,omidon.