Generic

Olmesartan Medoxomil 20mg and Hydrochlorothiazide 12.50mg

Description

Olmesan Plus is a combination drug used to manage hypertension. It effectively lowers blood pressure by combining olmesartan, an angiotensin II receptor blocker (ARB), with Hydrochlorothiazide, a thiazide diuretic.

Benefits

• It helps control high blood pressure when a single medication is insufficient.
• Reduces risks of heart attacks, strokes, and kidney failure.
• Supports improved blood flow and overall cardiovascular health.

Ingredients

• Olmesartan Medoxomil: 20mg
• Hydrochlorothiazide: 12.50mg

Uses and Doses

Uses:
Indicated for the treatment of essential hypertension in adults, particularly those not adequately controlled with Olmesartan alone.

Dosage:

• Starting Dose: 20mg/12.5mg once daily.
• Maximum Dose: 40mg/25mg daily.
• Dose adjustments should be made every 2-4 weeks based on response.

Side Effects

Common side effects include dizziness, nausea, diarrhea, headache, electrolyte imbalances, increased uric acid, and hypotension. Rarely, severe allergic reactions or renal complications may occur.

How to Use

Take one tablet daily, preferably in the morning, with or without food. Avoid crushing or chewing the tablet. Maintain a fixed schedule for consistency.

Pregnancy & Lactation

It is not recommended during pregnancy or breastfeeding. It is classified as Category C in the first trimester and Category D in the second and third trimesters due to the risk of fetal harm.

Precautions and Warnings

• Monitor for dehydration, low sodium, or hypotension, particularly after the first dose.
• Use caution in patients with kidney or liver impairment.
• Not suitable for patients with severe renal impairment (CrCl <30 mL/min).
• Avoid use in pregnancy and lactation.

Safety Information

Regular monitoring of kidney function and electrolytes is recommended. Avoid use alongside certain drugs like NSAIDs, lithium, or aliskiren.

Indications

Treats essential hypertension, especially in cases where monotherapy with Olmesartan is insufficient.

Pharmacology

Hydrochlorothiazide promotes water and sodium excretion, reducing fluid overload. Olmesartan blocks the action of angiotensin II, reducing vasoconstriction and lowering blood pressure.

Therapeutic Class

Combined antihypertensive preparations.

Storage Conditions

Store in a cool, dry place away from light. Keep out of children’s reach.

FAQ

1. What is Olmesan Plus used for?
   To treat high blood pressure and reduce associated risks like strokes and heart attacks.
2. Can it be taken during pregnancy?
   No, it is unsafe during pregnancy.
3. How should I take Olmesan Plus?
   Take as prescribed, once daily, preferably in the morning.

Disclaimer

The information is for educational purposes only. Always consult a healthcare professional before starting or stopping any medication.

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