Generic
Naproxen Sodium 375mg, Esomeprazole 20mg

Description
Novoxen 375 is a combination tablet from Orion Pharma Ltd., formulated with Naproxen Sodium and Esomeprazole. It helps in reducing inflammation and pain while protecting the stomach lining from ulcers caused by NSAID use.

Benefits
Novoxen 375 provides dual-action relief: Naproxen reduces pain and inflammation, while Esomeprazole minimizes the risk of gastric ulcers. It is highly effective for long-term arthritis management and pain-related conditions.

Ingredients
Each tablet contains 375 mg of Naproxen Sodium and 20 mg of Esomeprazole Magnesium in a dual-layer format for optimal absorption.

Uses and Doses
Used to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis and to reduce the risk of NSAID-related gastric ulcers.
Adults: One tablet twice daily.
Adolescents (12+ years, 38–50kg): One tablet twice daily.
Use the lowest effective dose for the shortest duration based on the doctor's advice.

Side Effects
Common side effects include headache, nausea, vomiting, indigestion, flatulence, stomach pain, diarrhea, and flu-like symptoms. Severe effects like erosive gastritis or ulcers are rare but possible.

How to Use
Swallow the tablet whole with food to reduce stomach upset. Do not crush or chew. Follow your doctor’s dosage instructions strictly.

Pregnancy & Lactation
It is not recommended in late pregnancy due to the risk of premature ductus arteriosus closure. Nursing mothers should avoid due to Naproxen component. Use only if prescribed by a doctor.

Precautions and Warnings
Use with caution in patients with cardiovascular disease, hypertension, or fluid retention. Avoid in cases of allergy to NSAIDs or proton-pump inhibitors.

Safety Information
Do not self-medicate or exceed the recommended dose. Avoid alcohol during medication. Inform your doctor of all other ongoing medications before starting Novoxen 375.

Indications
Relieves symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It also helps in reducing the risk of NSAID-induced gastric ulcers.

Pharmacology
The Esomeprazole layer dissolves first in the stomach to reduce acid, protecting the stomach lining. Naproxen is then absorbed in the intestine to act on inflammation and pain.

Therapeutic Class
Non-steroidal anti-inflammatory drugs (NSAIDs), drugs for rheumatoid arthritis and osteoarthritis.

Storage Conditions
Store below 30°C in a cool, dry place away from light and out of children’s reach.

3 FAQ
Q: Can I take Novoxen 375 on an empty stomach?
No, take it with food to avoid stomach upset.
Q: Is Novoxen 375 safe during pregnancy?
Avoid during late pregnancy. Consult your doctor for safety.
Q: Can I drink alcohol while taking this medicine?
No, alcohol increases stomach issues and may cause drowsiness.

Disclaimer
This information is for general awareness only. Always follow your healthcare provider’s instructions. Self-medication may cause harm.

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