Generic
Micronised Diosmin 450mg + Hesperidin 50mg

Description
Normanal 500 is a phlebotomist and vascular-protecting drug used to treat venous insufficiency and hemorrhoidal diseases. Manufactured by Renata Pharma Ltd, it enhances venous tone, improves blood flow, and alleviates symptoms of hemorrhoidal attacks and chronic venous insufficiency. It also combats inflammation, strengthens capillaries, and normalizes capillary permeability.

Benefits
Normanal 500 provides relief from hemorrhoidal symptoms, reduces venous distensibility and capacitance, and improves venous tone. It also protects microcirculation, reduces inflammation, and supports capillary strength.

Ingredients
Each tablet contains:

• Micronized Diosmin 450mg
• Hesperidin 50mg

Uses and Doses
Normanal 500 is used in the treatment of acute and chronic hemorrhoidal attacks and chronic venous insufficiency.

• Acute hemorrhoids: 3 tablets twice daily for 4 days, followed by 2 tablets twice daily for 3 days.
• Chronic hemorrhoids: 1 tablet twice daily.
• Chronic venous insufficiency: 1 tablet twice daily for 7 days, duration based on severity.

Side Effects
Common side effects include stomach pain, nausea, itching, dizziness, diarrhea, and skin redness. These symptoms are usually mild and resolve over time. In rare cases, neurovegetative disorders may occur but do not require discontinuation of the treatment.

How to Use
Take Normanal 500 with food as prescribed by your doctor. Swallow the tablet whole, without chewing, crushing, or breaking it. For optimal results, continue the treatment for the prescribed duration, even if symptoms improve earlier.

Pregnancy & Lactation
No harmful effects have been reported in human studies, although breastfeeding during treatment is not recommended due to the lack of data on excretion in breast milk. Always consult your doctor before use during pregnancy or breastfeeding.

Precautions and Warnings
Consult your doctor if hemorrhoidal symptoms persist beyond 15 days. If you are allergic to any ingredient in the product, avoid its use. Chronic venous insufficiency should be diagnosed and managed by a physician.

Safety Information
Store the product in a cool, dry place below 30°C, away from light and moisture. Keep out of children's reach.

Indications
Normanal 500 is indicated for treating acute hemorrhoidal attacks, chronic hemorrhoidal disease, and chronic venous insufficiency of the lower limbs.

Pharmacology
Normanal contains Diosmin and Hesperidin, which enhance venous tone and protect the vascular system by reducing venous capacitance and distensibility. They also decrease venous emptying time and inflammation by inhibiting leukocyte activation and the release of inflammatory mediators.

Therapeutic Class
Phlebotomy and Vascular Protecting Preparations.

Storage Conditions
Store in a cool, dry place below 30°C, away from moisture and light. Keep out of reach of children.

3 FAQ

1. Can Normanal 500 be taken during pregnancy?
   • While no harmful effects have been reported in human studies, it’s best to consult a doctor before use during pregnancy.
2. How long should I take Normanal for chronic venous insufficiency?
   • Treatment duration may vary from 2-6 months, depending on the severity.
3. Can I stop taking Normanal if my symptoms improve?
   • Continue taking it for the prescribed duration, even if symptoms improve, to prevent recurrence.

Disclaimer
This information is provided for educational purposes only and does not substitute professional medical advice. Always consult your healthcare provider for personalized advice and treatment.

Keywords: Normanal 500, Micronised Diosmin, Hesperidin, Hemorrhoid treatment, Venous insufficiency, Vascular protection, Renata Pharma, Chronic hemorrhoids, Acute hemorrhoids, Diosmin Hesperidin, Phlebotonic drug, Venous tone, Microcirculation, Venous distensibility, Capillary strength, Inflammation reduction, Hemorrhoid relief, Capillary resistance, Venous emptying time, Vascular protection.