Generic

Pregabalin

Description

Neurolin 75 is a capsule produced by Square Pharmaceuticals Limited, containing Pregabalin, which is commonly used for treating neuropathic pain, epilepsy, and fibromyalgia. It is also effective for managing post-herpetic neuralgia and nerve pain associated with diabetic peripheral neuropathy. This medication helps alleviate symptoms by modulating calcium channels in the central nervous system.

Benefits

Neurolin 75 offers relief from neuropathic pain, assists in managing seizures, reduces widespread pain in fibromyalgia patients, and helps with anxiety symptoms. Its effective treatment of diabetic peripheral neuropathy and post-herpetic neuralgia makes it a valuable option for nerve-related pain conditions.

Ingredients

Active Ingredient: Pregabalin
Inactive Ingredients: Excipients commonly used in pharmaceutical formulations for capsules.

Uses and Doses

• Neuropathic Pain: Initial dose of 50 mg three times daily, adjustable up to 300 mg/day.
• Post-Herpetic Neuralgia: Starting with 75 mg twice daily, increased as needed to 150-300 mg/day.
• Partial Seizures: 150-600 mg/day divided into two or three doses.
• Fibromyalgia: Recommended dose ranges between 300 to 450 mg/day, starting with 75 mg twice daily.
• Spinal Cord Injury: Starting dose of 75 mg twice daily, adjustable up to 600 mg/day.

Side Effects

Common side effects include dizziness, blurred vision, dry mouth, weight gain, sleepiness, and swelling (edema). In rare cases, Pregabalin may cause confusion, mood swings, and suicidal thoughts.

How to Use

Take Neurolin 75 as advised by your doctor, with or without food. It is important to follow the prescribed dosage and maintain a regular schedule to ensure the medication’s effectiveness. Do not stop taking it abruptly without consulting your doctor.

Pregnancy & Lactation

Pregnancy Category C. Pregabalin should only be used if the benefits outweigh the risks to the fetus. It is unclear if Pregabalin is excreted in human milk; therefore, it should only be used in nursing mothers if absolutely necessary.

Precautions and Warnings

Pregabalin may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also interact with alcohol, increasing drowsiness. Use caution if you have a history of angioedema or severe cardiovascular disease.

Safety Information

Do not discontinue Pregabalin suddenly as it may lead to withdrawal symptoms such as insomnia, nausea, and headaches. Gradual tapering over at least one week is recommended. Regular monitoring for signs of suicidal thoughts and mood changes is essential.

Indications

Neurolin 75 is used for the treatment of neuropathic pain, partial seizures in adults, fibromyalgia, and post-herpetic neuralgia. It is also prescribed for neuropathic pain associated with spinal cord injury.

Pharmacology

Pregabalin, a derivative of gamma-aminobutyric acid (GABA), works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces neurotransmitter release and diminishes pain signaling.

Therapeutic Class

Adjunct anti-epileptic drugs

Storage Conditions

Store Neurolin 75 in a cool and dry place, below 30°C, protected from light and moisture. Keep out of reach of children.

3 FAQ

1. How long does it take for Neurolin 75 to work?
It may take a few weeks to notice improvement, depending on the condition being treated.

2. Can I stop taking Neurolin 75 abruptly?
No, stopping suddenly can cause withdrawal symptoms. Always consult your doctor for a gradual reduction plan.

3. Is it safe to take Neurolin 75 while pregnant?
Neurolin 75 is only recommended during pregnancy if the benefits justify the potential risks. Consult your doctor before use.

Disclaimer

This information is for educational purposes only. Consult a healthcare provider before starting any medication. Pregabalin can have side effects that vary from person to person, and it is crucial to follow medical advice for proper use and dosage.

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