Generic

Neso 500/20 combines Naproxen Sodium (500mg) and Esomeprazole Magnesium (20mg), providing an effective treatment for managing arthritis-related symptoms and reducing the risk of NSAID-related gastric ulcers.

Description

Neso 500/20 by Aristopharma Ltd. is a combination tablet formulated to alleviate pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis while reducing the risk of gastric ulcers. This dual-layered tablet releases esomeprazole in the stomach and naproxen in the intestines for effective symptom control and gastric protection.

Benefits

Neso 500/20 is beneficial for patients experiencing arthritis pain as it combines the anti-inflammatory properties of naproxen with the gastric protection provided by esomeprazole. This dual-action tablet not only relieves pain and inflammation but also minimizes the risk of NSAID-induced gastric issues.

Ingredients

Each Neso 500/20 tablet contains 500 mg of Naproxen Sodium and 20 mg of Esomeprazole Magnesium. Naproxen Sodium is an NSAID, while Esomeprazole Magnesium is a proton pump inhibitor.

Uses and Doses

Neso 500/20 is used to treat rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Adults are advised to take one tablet twice daily. Adolescents weighing more than 50 kg may use the same dosage. Tablets should be taken at least 30 minutes before meals and should not be split, chewed, or crushed.

Side Effects

While Neso 500/20 is generally well-tolerated, potential side effects include nausea, gastritis, diarrhea, epigastric pain, and gastric ulcer. Serious side effects are rare but may include erosive gastritis and dyspepsia.

How to Use

Take Neso 500/20 tablets as prescribed by a healthcare provider. Swallow the tablet whole at least 30 minutes before meals to ensure optimal absorption. Do not crush or chew the tablet, as it may interfere with its release mechanism.

Pregnancy & Lactation

Neso 500/20 is categorized as pregnancy category C and should be avoided during the third trimester due to the risk of premature closure of the ductus arteriosus. Nursing mothers are advised against using this tablet due to the potential risks associated with naproxen.

Precautions and Warnings

Patients with cardiovascular disease or a history of fluid retention should use Neso 500/20 cautiously. It is contraindicated in patients with known allergies to any of its components and should not be used in the perioperative period of coronary artery bypass surgery.

Safety Information

Patients should inform their healthcare provider of any existing health conditions before taking Neso 500/20. Combining this medication with other NSAIDs or anticoagulants may increase bleeding risks. Avoid alcohol and smoking during the treatment course to reduce the risk of adverse effects.

Indications

Neso 500/20 is indicated for relieving symptoms associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also indicated to reduce the risk of NSAID-related gastric ulcers in at-risk patients.

Pharmacology

The unique formulation of Neso 500/20 provides immediate release of esomeprazole in the stomach for gastric protection, followed by the release of naproxen in the intestines for pain relief. Naproxen inhibits prostaglandin synthesis to alleviate pain, while esomeprazole blocks acid production in the stomach.

Therapeutic Class

Neso 500/20 belongs to the therapeutic classes of drugs used for osteoarthritis, rheumatoid arthritis, and non-steroidal anti-inflammatory drugs (NSAIDs).

Storage Conditions

Store Neso 500/20 below 30°C, away from moisture and light. Keep out of reach of children.

FAQ

1. Can I split or crush Neso 500/20 tablets?
No, Neso 500/20 tablets should not be split, chewed, or crushed to maintain their efficacy and controlled release mechanism.

2. How should I take Neso 500/20 tablets?
Take the tablet whole at least 30 minutes before meals, with a glass of water, as directed by your healthcare provider.

3. Are there any foods I should avoid while taking Neso 500/20?
Avoid high-fat meals around the time of taking this tablet, as they may delay absorption of the medication.

Disclaimer

This information is provided for general knowledge and should not replace medical advice from healthcare professionals. Consult a doctor before using Neso 500/20, especially if you have pre-existing health conditions or are taking other medications.

Keywords: Naproxen, Esomeprazole, arthritis relief, gastric protection, NSAIDs, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, Aristopharma, dual-action tablet, pain relief, anti-inflammatory, gastric ulcer prevention, proton pump inhibitor, arthritis medication, stomach protection, combination therapy, Naproxen Sodium, Esomeprazole Magnesium, joint pain.