Generic
Motigut contains Domperidone Maleate, a medication used primarily as an antiemetic and motility stimulant. It’s effective in managing symptoms related to delayed gastric emptying, including nausea and vomiting.

Description
Motigut is a tablet manufactured by Square Pharmaceuticals Limited, featuring 10mg of Domperidone Maleate. This medication functions by blocking dopamine receptors, which helps in reducing nausea and promotes gastrointestinal motility.

Benefits
Motigut effectively addresses discomfort associated with delayed gastric emptying and reflux, helping alleviate symptoms like nausea, vomiting, and epigastric fullness. It also aids in enhancing digestive function by stimulating peristalsis.

Ingredients
Each Motigut tablet contains 10mg of Domperidone Maleate as the active ingredient.

Uses and Doses
Motigut is indicated for adults and children to manage symptoms such as nausea, vomiting, and dyspepsia. Adults typically take 10-20 mg every 6-8 hours before meals, while children’s doses are calculated based on body weight. In cases of acute nausea, adults may require 20 mg every 6-8 hours, with a maximum treatment duration of 12 weeks.

Side Effects
Common side effects may include hyperprolactinemia, dry mouth, headache, and gastrointestinal discomfort. In rare cases, patients may experience extrapyramidal reactions or dermatological reactions.

How to Use
Take Motigut tablets 15-30 minutes before meals. Adults generally take 1-2 tablets every 6-8 hours, while doses for children depend on body weight. Avoid exceeding the maximum dose of 80 mg daily.

Pregnancy & Lactation
The safety of Motigut during pregnancy is not established, so use it only if needed. While it may support lactation, the drug is minimally excreted in breast milk.

Precautions and Warnings
Use with caution in children, particularly due to the risk of extrapyramidal effects. Patients with hepatic impairment should also use caution due to the drug’s extensive liver metabolism.

Safety Information
Motigut is contraindicated in patients with gastrointestinal bleeding, mechanical obstruction, or known sensitivity to Domperidone. It should not be administered in cases where gastrointestinal stimulation may be dangerous.

Indications
Motigut treats symptoms like nausea, vomiting, epigastric discomfort, and fullness associated with delayed gastric emptying. It’s also useful in Parkinson’s disease-related sickness and radiological studies requiring accelerated barium transit.

Pharmacology
Motigut works as a dopamine antagonist, blocking receptors in the Chemoreceptor Trigger Zone (CTZ), resulting in antiemetic effects and improved gastrointestinal motility. Its poor blood-brain barrier penetration minimizes central side effects.

Therapeutic Class
Motigut belongs to motility stimulants and dopamine antagonists.

Storage Conditions
Store below 30°C, protected from light and moisture, and keep out of reach of children.

FAQ

1. Can I take Motigut for motion sickness?
   Motigut primarily treats gastrointestinal-related nausea and vomiting rather than motion sickness.
2. Is Motigut safe for long-term use?
   Motigut is usually recommended for short-term treatment, with a maximum duration of 12 weeks for acute nausea cases.
3. Can Motigut be taken without a prescription?
   No, Motigut requires a prescription for safe and effective use.

Disclaimer
This information is intended for educational purposes only and should not replace medical advice from a healthcare provider. Always follow your doctor’s guidance regarding medications.

Keywords: Motigut, Domperidone, nausea treatment, vomiting relief, gastroprokinetic, delayed gastric emptying, Square Pharmaceuticals, antiemetic, dopamine antagonist, GI motility, prescription medication, dyspepsia, gastric reflux, upper stomach pain, epigastric discomfort, pediatric nausea, Parkinson’s nausea, barium transit, gastric motility, esophageal sphincter.