Generic
Medroxyprogesterone Acetate

Description
Medrogest 10 is a tablet containing 10 mg of Medroxyprogesterone Acetate, used as a progestin to treat secondary amenorrhea and abnormal uterine bleeding caused by hormonal imbalance. It is also effective in reducing the incidence of endometrial hyperplasia in nonhysterectomized postmenopausal women receiving estrogen therapy.

Benefits
Medrogest 10 helps regulate the menstrual cycle, prevents abnormal uterine bleeding, and manages hormonal imbalances. It also decreases the risk of endometrial hyperplasia in postmenopausal women on estrogen therapy, reducing the chances of uterine-related complications.

Ingredients
Active Ingredient: Medroxyprogesterone Acetate 10mg
Inactive Ingredients: [Please list inactive ingredients if provided]

Uses and Doses

• Abnormal Uterine Bleeding: Take 5-10 mg daily for 5-10 days, starting on the 16th or 21st day of the menstrual cycle.
• Secondary Amenorrhea: Take 5-10 mg daily for 5-10 days.
  For both conditions, withdrawal bleeding usually occurs within 3-7 days after discontinuation.

Side Effects
Common side effects include irregular uterine bleeding, breakthrough bleeding, spotting, amenorrhea, nausea, headache, and breast tenderness. Serious side effects like thromboembolic disorders, jaundice, and allergic reactions may occur.

How to Use
Medrogest 10 is taken orally with or without food, as prescribed by a physician. Consistent use for 5-10 days is essential for achieving the desired outcome. Follow the exact dosage and administration schedule provided by your healthcare professional.

Pregnancy & Lactation
Medroxyprogesterone Acetate should not be used during pregnancy, as it may increase risks for certain fetal conditions. It is also not recommended during breastfeeding as traces of the drug can pass into breast milk.

Precautions and Warnings
Use cautiously in women with liver disease, cardiovascular conditions, or a history of thromboembolic disorders. Regular monitoring of blood pressure and triglyceride levels is necessary. Progestins may exacerbate existing conditions such as asthma, diabetes, and epilepsy.

Safety Information
Do not use Medrogest 10 if you are pregnant, have active liver disease, have a history of breast cancer, or have active thromboembolic conditions. Keep out of reach of children and avoid storing above 30°C.

Indications
Medrogest 10 is indicated for treating secondary amenorrhea, abnormal uterine bleeding due to hormonal imbalance, and reducing endometrial hyperplasia risk in postmenopausal women receiving estrogen therapy.

Pharmacology
Medroxyprogesterone Acetate transforms proliferative endometrium into secretory endometrium. It has androgenic and anabolic effects, but no significant estrogenic activity. Oral administration at recommended doses does not inhibit follicular maturation or ovulation.

Therapeutic Class
Female sex hormones.

Storage Conditions
Store below 30°C, away from light and moisture. Keep it in a tightly closed container and out of children's reach.

FAQ

1. Can Medrogest 10 be used during pregnancy?
   No, it is contraindicated in pregnancy due to potential fetal risks.
2. What are the common side effects of Medrogest 10?
   Common side effects include abnormal uterine bleeding, nausea, and headache.
3. When will withdrawal bleeding start after stopping Medrogest 10?
   Withdrawal bleeding typically occurs within 3-7 days after stopping the medication.

Disclaimer
The information provided here is for informational purposes only. Consult a healthcare professional for medical advice, diagnosis, or treatment. Do not use this information to self-diagnose or self-treat any health conditions.

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