Generic:

Fluconazole

Description:

Lucan-R 150 contains Fluconazole, an antifungal medication used to treat various fungal infections. Manufactured by Renata Limited, it works by inhibiting fungal enzymes necessary for the production of the fungal cell membrane.

Benefits:

Lucan-R 150 effectively treats vaginal, oropharyngeal, esophageal, and systemic candida infections, including candidemia and cryptococcal meningitis. It is also used for prophylaxis in patients undergoing bone marrow transplants.

Ingredients:

Each capsule contains 150 mg of Fluconazole.

Uses and Doses:

Lucan-R 150 is indicated for various fungal infections, including vaginal candidiasis (single dose of 150 mg), oropharyngeal candidiasis (200 mg on the first day followed by 100 mg daily), and cryptococcal meningitis (400 mg on the first day followed by 200 mg daily). Dosing varies for systemic candida infections and bone marrow transplant prophylaxis.

Side Effects:

Common side effects include nausea, vomiting, diarrhea, headache, abdominal pain, and skin rashes. Fluconazole is generally well-tolerated, but allergic reactions may occur in rare cases.

How to Use:

Take Lucan-R 150 as directed by your physician. It can be taken with or without food. For vaginal candidiasis, a single 150 mg dose is recommended. For other infections, follow the dosing schedule prescribed.

Pregnancy & Lactation:

Fluconazole falls under FDA Pregnancy Category C. It should be avoided during pregnancy and lactation unless the benefits outweigh the potential risks to the fetus.

Precautions and Warnings:

Lucan-R 150 should be used with caution in patients with proarrhythmic conditions. It is contraindicated in individuals with known hypersensitivity to Fluconazole or related compounds.

Safety Information:

Lucan-R 150 may interact with other medications such as cyclosporin, phenytoin, warfarin, and rifampicin. Always consult your doctor regarding potential drug interactions.

Indications:

Lucan-R 150 is indicated for treating vaginal candidiasis, oropharyngeal and esophageal candidiasis, systemic candida infections, and cryptococcal meningitis. It can also be used for candida infections in the urinary tract and peritonitis.

Pharmacology:

Fluconazole, a triazole antifungal, works by inhibiting the cytochrome P-450 enzyme system, which is crucial for fungal ergosterol synthesis. This action weakens the fungal cell membrane, leading to the elimination of the infection.

Therapeutic Class:

Drugs for subcutaneous and mycoses.

Storage Conditions:

Store in a dry place away from light and heat. Keep out of reach of children.

3 FAQ:

Q1: Can Lucan-R 150 be taken during pregnancy?
A1: Fluconazole is FDA Category C, so it should be avoided unless the potential benefits outweigh the risks. Consult your doctor.

Q2: What is the usual dose for vaginal candidiasis?
A2: The usual dose for vaginal candidiasis is a single 150 mg dose.

Q3: Are there any drug interactions with Fluconazole?
A3: Yes, Fluconazole may interact with medications like cyclosporin, phenytoin, warfarin, and rifampicin. Consult your doctor before use.

Disclaimer:

The information provided is for educational purposes only. Always consult your healthcare provider before using any medication.

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