Generic

Linagliptin + Metformin Hydrochloride

Description

Lijenta-M 1000 is a combination of Linagliptin (2.5mg) and Metformin Hydrochloride (1000mg). It is used to manage blood sugar levels in adults with type 2 diabetes mellitus as an adjunct to diet and exercise. Manufactured by Nipro JMI Pharma Ltd, this combination targets glycemic control by regulating glucose production and enhancing insulin sensitivity.

Benefits

Lijenta-M 1000 helps control high blood sugar, reducing the risk of serious diabetes complications like kidney damage, blindness, heart attacks, and strokes. It can be taken alone or with other diabetes medications for improved glycemic control and overall well-being.

Ingredients

Linagliptin 2.5mg, Metformin Hydrochloride 1000mg

Uses and Doses

For glycemic control in type 2 diabetes patients. The recommended starting dose depends on prior treatment, with a maximum of 2.5mg Linagliptin and 1000mg Metformin twice daily. The dose should be taken with meals to minimize gastrointestinal side effects.

Side Effects

Common side effects include diarrhea, nausea, vomiting, upset stomach, headache, nasal congestion, sore throat, and hypoglycemia (especially when used with insulin or sulfonylureas).

How to Use

Take Lijenta-M 1000 with food, as advised by your doctor, and at the same time each day to maintain consistent blood sugar control. Swallow whole without chewing or crushing.

Pregnancy & Lactation

There are no sufficient studies on its safety during pregnancy and breastfeeding. Use only if clearly needed, and consult with a healthcare provider before use.

Precautions and Warnings

Monitor for lactic acidosis, pancreatitis, and hypoglycemia. Discontinue use before surgery or radiologic procedures requiring iodinated contrast. Monitor renal function annually, especially in patients at risk of kidney impairment.

Safety Information

Not suitable for patients with type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver dysfunction. Avoid alcohol, as it can increase the risk of lactic acidosis.

Indications

Used for the treatment of type 2 diabetes mellitus as part of a comprehensive program involving diet and exercise.

Pharmacology

Linagliptin inhibits DPP-4, increasing incretin hormone levels, which promote insulin secretion and reduce glucagon levels. Metformin decreases hepatic glucose production, enhances insulin sensitivity, and lowers plasma glucose levels without causing hypoglycemia.

Therapeutic Class

Combination Oral Hypoglycemic Agents

Storage Conditions

Store in a cool, dry place below 30°C, away from light and moisture. Keep out of reach of children.

3 FAQ

1. What happens if I miss a dose?
Take the missed dose as soon as you remember, but skip it if it's almost time for the next dose. Do not double up.

2. Can I take Lijenta-M 1000 with other diabetes medications?
Yes, but you should consult your doctor to adjust the dosage and avoid hypoglycemia.

3. Can I take this medication if I have kidney issues?
This medication is not recommended for patients with significant kidney impairment due to the risk of lactic acidosis.

Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Consult a doctor for diagnosis and treatment options.

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