Generic
Letrozole 2.50mg

Description
Letrozole is a nonsteroidal aromatase inhibitor used primarily to treat breast cancer in postmenopausal women. It works by reducing estrogen production, inhibiting cancer cell growth that relies on estrogen. Manufactured by Renata Pharma Ltd., it’s available in 2.5 mg tablets.

Benefits
Letrozole provides effective treatment for hormone receptor-positive breast cancer, offers a non-invasive oral therapy option, reduces tumor progression, and can be used in infertility treatment due to its ability to stimulate ovulation.

Ingredients
Active ingredient: Letrozole 2.50mg.

Uses and Doses
Letrozole is prescribed to treat breast cancer, particularly in postmenopausal women. It is taken orally, once daily, at a dose of 2.5 mg. Doses remain consistent for elderly patients and those with mild to moderate hepatic impairment.

Side Effects
Common side effects include hot flashes, fatigue, increased sweating, and elevated cholesterol levels. Severe side effects may include vaginal bleeding, swelling, and bone thinning.

How to Use
Take Letrozole exactly as prescribed by your doctor. It can be taken with or without food but should be taken at the same time every day. Do not double doses if a dose is missed.

Pregnancy & Lactation
Letrozole is contraindicated in pregnancy and lactation due to potential risks, including teratogenicity and fetotoxicity. It is not recommended for premenopausal women or those breastfeeding.

Precautions and Warnings
Exercise caution in patients with severe hepatic or renal impairment, osteoporosis, or cardiovascular conditions. Letrozole may impair concentration, so avoid operating machinery.

Safety Information
Avoid using Letrozole if allergic to any of its components. Regular monitoring of cholesterol levels and bone density is advised during treatment.

Indications
Letrozole is indicated for the treatment of hormone receptor-positive breast cancer in postmenopausal women, as well as for infertility caused by anovulation.

Pharmacology
Letrozole competitively binds to the aromatase enzyme, blocking estrogen synthesis. This reduction in estrogen levels prevents the growth of estrogen-dependent breast cancer cells.

Therapeutic Class
Hormonal chemotherapy agents are used primarily for breast cancer treatment.

Storage Conditions
Store below 30°C, away from moisture and light. Keep out of reach of children.

3 FAQ

1. Can Letrozole be taken with food? Yes, it can be taken with or without food.
2. What should I do if I miss a dose? Take the missed dose as soon as possible unless it’s almost time for the next dose.
3. What are the severe side effects? Severe side effects include vaginal bleeding, bone thinning, and swelling of the face.

Disclaimer
The information provided here is for educational purposes only. Consult your healthcare provider for medical advice before starting any treatment. Always follow your doctor's instructions regarding the use of Letrozole.

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