Generic
The generic name for Lebac 500 is Cephradine.

Description
Lebac 500 is an antibiotic capsule that contains Cephradine, an effective first-generation cephalosporin used to combat infections caused by both Gram-positive and Gram-negative bacteria. It is produced by Square Pharmaceuticals Ltd. and is designed to treat various bacterial infections, particularly those in the respiratory, urinary, and skin tissues.

Benefits
Lebac 500 treats a wide array of bacterial infections by targeting bacteria responsible for respiratory, urinary, and skin infections. It provides a comprehensive solution with both bactericidal and broad-spectrum properties, including effectiveness against penicillin-resistant bacteria.

Ingredients
The main ingredient in Lebac 500 is Cephradine 500 mg, a broad-spectrum antibiotic with bactericidal effects.

Uses and Doses
Lebac 500 is used to treat infections in the respiratory tract, urinary system, skin, and soft tissues.

• Adults: 500 mg four times daily for urinary tract infections or 1g twice daily, adjusted per infection severity.
• Children: 25-50 mg/kg per day in divided doses, with otitis media requiring 75-100 mg/kg daily.
• Elderly: Standard adult dosage, with adjustments for renal or hepatic impairment.

Side Effects
Common side effects may include drowsiness, muscle weakness, reduced alertness, headache, and gastrointestinal disturbances. Some may experience hypersensitivity reactions like rashes and urticaria, and rarely, blood disorders or interstitial nephritis may occur.

How to Use
Take Lebac 500 with water as directed by a healthcare provider. Dosage and frequency depend on infection type and severity. Avoid alcohol, as it may amplify sedative effects.

Pregnancy & Lactation
Though animal studies show no teratogenicity, safety in pregnancy is unproven. Cephradine can be secreted in breast milk and is not recommended for breastfeeding women.

Precautions and Warnings
Patients allergic to cephalosporins or penicillins should use caution. Long-term use may lead to superinfections by resistant organisms. Cephradine may yield a false positive in certain Coombs’ and urine glucose tests.

Safety Information
Store Cephradine suspension fresh; use within 7 days at room temperature or within 14 days refrigerated. Keep out of children’s reach and use only as prescribed by a healthcare provider.

Indications
Lebac 500 is indicated for treating respiratory tract infections, urinary tract infections, and skin infections caused by various bacterial organisms sensitive to Cephradine.

Pharmacology
Cephradine works by disrupting bacterial cell walls, resulting in lysis. It is effective against penicillinase-producing staphylococci, making it a valuable tool for combating resistant bacteria.

Therapeutic Class
Lebac 500 belongs to the first-generation cephalosporin antibiotic class, known for broad-spectrum bactericidal activity.

Storage Conditions
Store reconstituted suspension at ambient temperature for up to 7 days or refrigerated for 14 days. Injectables retain efficacy for 12 hours at 5°C and should not be used past their expiry date.

3 FAQ

1. What infections does Lebac 500 treat?
   Lebac 500 is effective for respiratory, urinary tract, and skin infections caused by both Gram-positive and Gram-negative bacteria.
2. Can I take Lebac 500 during pregnancy?
   Although animal studies do not show teratogenicity, Cephradine is secreted in breast milk and is best avoided during pregnancy and breastfeeding.
3. How should I store Cephradine suspension?
   The suspension should be stored fresh and used within 7 days at room temperature or 14 days if refrigerated.

Disclaimer
Always consult a healthcare provider before using Lebac 500, especially if you have allergies to antibiotics. The information provided here is for educational purposes only and is not a substitute for professional medical advice.

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