Generic
Itraconazole

Description
Itra 100 is an antifungal medication containing 100mg of Itraconazole, produced by Square Pharmaceuticals Limited. It treats fungal infections by disrupting the cell membrane of fungi, preventing their growth and effectively controlling infections in areas such as the mouth, throat, and skin, including fingernails and toenails.

Benefits
Itra 100 provides effective relief from fungal infections by targeting cell membrane synthesis in fungi. Its wide application includes treating candidiasis, tinea infections, and systemic infections. It’s beneficial for patients needing long-term antifungal treatment, such as those with immunocompromised systems.

Ingredients
Active ingredient: Itraconazole 100mg.

Uses and Doses
Itra 100 is used for treating fungal infections, including candidiasis, tinea pedis, tinea cruris, and systemic infections. Dosage varies based on the infection's type and severity. For instance, for vulvovaginal candidiasis, the recommended dose is 200 mg twice daily for one day, while for onychomycosis, a prolonged course of 200 mg daily is suggested for three months. Doses may be modified for patients with specific conditions or when treating children.

Side Effects
Common side effects include nausea, headache, dizziness, and abdominal pain. In rare cases, patients may experience liver enzyme elevations, menstrual disturbances, allergic reactions, or Stevens-Johnson syndrome. Prolonged usage may cause hair loss, edema, and hypokalemia.

How to Use
Take Itra 100 with food, preferably immediately after a meal. Swallow the capsule whole without crushing or chewing it. For best results, follow your doctor’s prescribed dosage schedule, even if symptoms subside early. Avoid taking antacids within two hours of taking this medication to ensure proper absorption.

Pregnancy & Lactation
Itra 100 is not recommended during pregnancy and lactation, as it may harm the fetus or affect breast milk. Consult with a healthcare provider before use if you are pregnant or planning to become pregnant.

Precautions and Warnings
Patients with liver function abnormalities should have regular liver tests, especially during extended treatments. Those with a history of congestive heart failure, renal insufficiency, or other cardiovascular conditions should consult a doctor before using this medication. Discontinue use and consult your doctor if symptoms of heart failure appear.

Safety Information
Patients should use effective contraceptive methods while taking Itra 100 to prevent pregnancy. Avoid driving or operating heavy machinery if experiencing dizziness or blurred vision. Discuss any current medications with your doctor to avoid interactions.

Indications
Itra 100 is indicated for treating fungal infections such as candidiasis, tinea pedis, tinea cruris, pityriasis versicolor, and systemic infections, including aspergillosis and cryptococcosis.

Pharmacology
Itraconazole is an oral triazole antifungal that inhibits Cytochrome P450 enzymes, impairing ergosterol synthesis in fungal cell membranes. This inhibition disrupts membrane permeability and enzyme activity, resulting in abnormal cell growth and cell death.

Therapeutic Class
Drugs for subcutaneous and systemic mycoses.

Storage Conditions
Store Itra 100 in a cool, dry place away from direct sunlight. Keep out of reach of children.

FAQ

1. What should I do if I miss a dose?
   Take the missed dose as soon as possible. Skip it if it’s almost time for your next dose. Do not double the dose.
2. Can I use Itra 100 while pregnant?
   Itra 100 is not recommended during pregnancy. Consult your doctor for alternatives if pregnant.
3. Are there food or drug interactions to consider?
   Avoid antacids and certain medications like warfarin and cyclosporine while taking Itra 100. Consult your doctor for a comprehensive list of interactions.

Disclaimer
This information is provided for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before beginning any new treatment.

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