Generic

Itopride Hydrochloride is a prokinetic agent primarily used to alleviate gastrointestinal symptoms associated with chronic gastritis. It enhances gastrointestinal motility by inhibiting dopamine D2 receptors and acetylcholinesterase, leading to increased acetylcholine concentrations.

Description

Itopride Hydrochloride, an effective dopamine-2 antagonist and acetylcholine esterase inhibitor, is designed to improve gastrointestinal motility. It helps in the treatment of gastrointestinal symptoms, including feelings of an enlarged abdomen, upper abdominal pain, anorexia, heartburn, nausea, and vomiting.

Benefits

• Enhances gastrointestinal motility.
• Increases acetylcholine concentrations, leading to improved peristalsis and gastric motility.
• Alleviates symptoms such as bloating, nausea, and heartburn.
• Accelerates gastric emptying and improves gastro-duodenal coordination.

Ingredients

The active ingredient in this medication is Itopride Hydrochloride. Other excipients may be present, which are necessary for the formulation of the tablet.

Uses and Doses

The usual adult dose for oral use is 50 mg of Itopride Hydrochloride taken three times daily before meals. The dosage may be adjusted based on the patient’s age and symptoms. It is not recommended for use in children and adolescents below 18 years of age.

Side Effects

Potential side effects include gastrointestinal disturbances, hepatic function disorders, jaundice, shock, and anaphylactoid reactions. Elderly patients are more susceptible to adverse reactions and should be closely monitored.

How to Use

Itopride Hydrochloride should be taken orally before meals. For medications in a press-through package (PTP), ensure the tablet is removed from the package to avoid ingestion of the packaging material, which could cause serious complications.

Pregnancy & Lactation

The safety of Itopride Hydrochloride during pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or nursing infant.

Precautions and Warnings

This drug enhances the action of acetylcholine and should be used cautiously, especially in patients prone to adverse reactions. It should not be consumed continuously without observed improvement in gastrointestinal symptoms. If adverse reactions occur, reduce the dosage or discontinue use.

Safety Information

Itopride Hydrochloride should be administered cautiously when used in combination with anticholinergic drugs, as they may reduce its efficacy. Patients with hypersensitivity to the active substance should not use this medication.

Indications

Indicated for the treatment of gastrointestinal symptoms in chronic gastritis, including upper abdominal pain, anorexia, heartburn, nausea, and vomiting.

Pharmacology

Itopride Hydrochloride acts as a dopamine-2 antagonist and acetylcholine esterase inhibitor, enhancing gastrointestinal motility by increasing acetylcholine concentrations. It promotes gastric emptying, increases lower esophageal sphincter pressure, and improves gastro-duodenal coordination.

Therapeutic Class

Gastrointestinal motility enhancer/prokinetic agent.

Storage Conditions

Store below 30°C in a cool, dry place, away from light. Keep all medications out of the reach of children.

FAQ

1. What is Itopride Hydrochloride used for?
   Itopride Hydrochloride is used to treat gastrointestinal symptoms associated with chronic gastritis.
2. Can children take Itopride Hydrochloride?
   The safety and efficacy of Itopride Hydrochloride in children and adolescents have not been established; therefore, it is not recommended for those below 18 years of age.
3. Are there any special precautions when taking Itopride Hydrochloride?
   Yes, elderly patients should be closely monitored for adverse reactions, and the medication should be used cautiously with anticholinergic drugs.

Disclaimer

The information provided here is for educational purposes only and does not substitute professional medical advice. Consult your healthcare provider before starting or stopping any medication.

Keywords: Itopride Hydrochloride, gastrointestinal motility, prokinetic agent, dopamine-2 antagonist, acetylcholine esterase inhibitor, gastritis treatment, nausea relief, heartburn relief, chronic gastritis, gastro-duodenal coordination, gastric emptying, upper abdominal pain, anorexia, nausea, vomiting, gastrointestinal symptoms, medication safety, elderly precautions, pediatric use, drug interactions.