Generic

Informet 500 contains Metformin Hydrochloride, a widely used oral antihyperglycemic agent for managing type 2 diabetes.

Description

Informet 500 is an extended-release tablet formulated with 500 mg of metformin hydrochloride. It helps regulate blood sugar levels in individuals with type 2 diabetes and significantly overweight patients by improving insulin sensitivity, reducing glucose production in the liver, and enhancing glucose uptake by cells.

Benefits

Informet 500 helps lower blood sugar levels in individuals with type 2 diabetes, reducing the risk of diabetes-related complications. It does not cause hypoglycemia when used alone and is often prescribed as a first-line treatment.

Ingredients

Each tablet contains 500mg of Metformin Hydrochloride as the active ingredient.

Uses and Doses

• Adults: The initial dose is 500mg twice daily or 850mg once daily with meals.
• Maximum dose: 2000mg per day, divided into smaller doses.
• Children (10 years and older): Start with 500mg twice daily with meals, gradually increasing the dose if necessary.
• Patients with renal impairment: Should not use if eGFR is below 30 mL/min.

For extended-release tablets, swallow whole without crushing or chewing.

Side Effects

Common side effects include nausea, vomiting, diarrhea, abdominal discomfort, and loss of appetite. Rare side effects include lactic acidosis, vitamin B12 deficiency, and taste disturbances.

How to Use

Take Informet 500 with meals to reduce gastrointestinal side effects. Extended-release tablets should be swallowed whole without breaking or chewing.

Pregnancy & Lactation

• Pregnancy: This should be avoided unless necessary. Insulin is preferred for managing diabetes during pregnancy.
• Breastfeeding: Metformin passes into breast milk but does not cause harm to the baby. However, consult a doctor before use.

Precautions and Warnings

Informet 500 should be used cautiously in patients with kidney impairment, liver disease, and those at risk of lactic acidosis. It may reduce vitamin B12 levels, so periodic monitoring is advised.

Safety Information

Patients with severe kidney disease, liver disease, or a history of metabolic acidosis should avoid Informet 500. Alcohol consumption should be limited while using this medication.

Indications

Informet 500 is indicated for managing type 2 diabetes mellitus, particularly in overweight patients when diet and exercise alone are insufficient.

Pharmacology

Metformin is a biguanide-class medication that helps lower blood sugar levels without causing hypoglycemia. It reduces glucose production in the liver, increases insulin sensitivity, and improves glucose uptake.

Therapeutic Class

Biguanides – Oral Antidiabetic Medications

Storage Conditions

Store below 30°C, away from moisture and light. Keep out of reach of children.

3 FAQ

1. Does Informet 500 cause weight loss?
   Yes, it may help with weight loss in overweight patients with diabetes.
2. Can Informet 500 cause low blood sugar?
   No, it does not cause hypoglycemia unless combined with insulin or sulfonylureas.
3. How long does Informet 500 take to work?
   It starts working within a few days, but full effects may take a few weeks.

Disclaimer

Informet 500 should only be used under medical supervision. Patients should not exceed the recommended dose without consulting a doctor. If symptoms of lactic acidosis occur, seek medical attention immediately.

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