Generic

Imucort 6 contains Deflazacort 6 mg, a glucocorticoid for inflammatory, autoimmune, and allergic conditions.

Description

Imucort 6 is a corticosteroid tablet manufactured by Ziska Pharmaceuticals Ltd. It has anti-inflammatory and immunosuppressive properties, effectively treating conditions like rheumatoid arthritis, asthma, allergies, and autoimmune disorders.

Benefits

Imucort 6 provides powerful anti-inflammatory effects, reduces immune overactivity, and relieves symptoms of autoimmune and inflammatory diseases. It also helps control allergic reactions and chronic inflammatory conditions while having a better safety profile than traditional steroids.

Ingredients

The active ingredient in Imucort 6 is Deflazacort 6 mg, a corticosteroid that inhibits prostaglandin synthesis and modulates immune responses.

Uses and Doses

Imucort 6 is prescribed for conditions such as:

• Asthma and allergic reactions
• Rheumatoid arthritis and juvenile arthritis
• Autoimmune diseases like lupus and sarcoidosis
• Dermatological conditions such as pemphigus and bullous pemphigoid
• Nephrotic syndrome and interstitial nephropathy
• Gastrointestinal diseases like Crohn’s disease and ulcerative colitis
• Hematologic disorders, including thrombocytopenic purpura and anemia
• Cancer-related conditions such as leukemia and lymphoma

Dosage:

• Acute conditions: Up to 120 mg/day, then reduced based on response.
• Rheumatoid arthritis: 3-18 mg/day, adjusted for symptoms.
• Asthma: 48-72 mg/day for acute attacks, then gradually reduced.
• Children: Dosage varies between 0.25-1.5 mg/kg/day, depending on the condition.
• Nephrotic syndrome: 1.5 mg/kg/day, with adjustments based on response.
• Bronchial asthma in children: 0.25-1 mg/kg every alternate day.

The dosage should be gradually tapered to prevent withdrawal effects.

Side Effects

Imucort 6 may cause mild to severe side effects, including:

• Gastrointestinal issues like nausea, bloating, and stomach pain
• Muscle weakness and joint pain
• Weight gain and fluid retention
• Increased blood pressure and blood sugar levels
• Mood changes, insomnia, and nervousness
• Skin issues such as acne, stretch marks, and atrophy
• Increased risk of infections due to immune suppression

Long-term use requires monitoring to prevent serious complications.

How to Use

Take Imucort 6 precisely as prescribed, with or after meals, to minimize stomach irritation. Swallow the tablet whole with water. If a dose is missed, take it as soon as possible, but do not double the next dose. Gradual dose reduction is required when stopping the medication.

Pregnancy & Lactation

Imucort 6 crosses the placenta and may affect fetal growth if used long-term. It should only be used during pregnancy if the benefits outweigh the risks. It is excreted in breast milk, but doses below 50 mg/day are unlikely to harm a nursing infant. Higher doses may cause adrenal suppression in newborns.

Precautions and Warnings

Caution is required for patients with:

• Heart disease, high blood pressure, or thromboembolic disorders
• Gastric ulcers, colitis, or digestive disorders
• Diabetes or family history of diabetes
• Osteoporosis or muscle weakness
• Kidney or liver impairment
• Mental health conditions like depression or anxiety

Long-term use can lead to adrenal suppression, requiring gradual withdrawal.

Safety Information

Deflazacort interacts with liver enzyme-inducing drugs like rifampicin, phenytoin, and carbamazepine, reducing its effectiveness. Ketoconazole and other liver enzyme inhibitors may increase potency, requiring dose adjustments. It may also alter blood thinner effects, requiring monitoring of clotting parameters.

Indications

Imucort 6 is indicated for:

• Autoimmune disorders like lupus, rheumatoid arthritis, and dermatomyositis
• Severe allergic reactions and asthma
• Inflammatory diseases affecting skin, joints, kidneys, and eyes
• Hematologic conditions like anemia and thrombocytopenia
• Cancer treatment support in leukemia and lymphoma
• Organ transplant immunosuppression

Pharmacology

Deflazacort inhibits phospholipase A2, reducing prostaglandin production. This decreases inflammation and immune activity. Deflazacort also prevents the release of immune-stimulating chemicals, reducing hypersensitivity reactions and autoimmune attacks.

Therapeutic Class

Imucort 6 belongs to the Glucocorticoids class and is used for immune suppression, inflammation control, and allergic reactions.

Storage Conditions

Store at below 30°C, away from light and moisture. Keep out of children’s reach.

3 FAQ

1. How long does Imucort 6 take to work?

   • It starts working within a few hours, with full effects seen in a few days.

2. Can Imucort Six be used for asthma long-term?

   • Yes, but only under a doctor’s supervision. Long-term use requires dose adjustment to minimize side effects.

3. Is Imucort 6 safe for children?

   • Yes, but doses should be carefully adjusted, and long-term use should be monitored for growth suppression risks.

Disclaimer

This information is for educational purposes only. Always consult a healthcare professional before using this medication, especially for long-term treatments or in pregnancy.

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