Generic

Pregabalin

Description

Gabarol 50 is a medication containing Pregabalin 50mg. It is used to manage neuropathic pain, post-herpetic neuralgia, and fibromyalgia and as an adjunct treatment for partial-onset seizures. Gabarol 50 regulates nerve signals in the central nervous system to reduce pain and seizures.

Benefits

Gabarol 50 relieves nerve pain associated with diabetic neuropathy, post-herpetic neuralgia, and spinal cord injuries. It also reduces pain sensitivity and improves sleep quality in fibromyalgia. Additionally, it is an effective adjunct therapy for epilepsy, helping to control seizures.

Ingredients

Each capsule contains 50mg of Pregabalin, an analoPregabalineurotransmitter gamma-aminobutyric acid (GABA), which modulates nerve activity and pain transmission.

Uses and Doses

For neuropathic pain, the starting dose is 50 mg three times a day, gradually increasing to a maximum of 300 mg per day based on response. For post-herpetic neuralgia, the dosage starts at 75 mg twice daily and may be increased to 300 mg daily. In epilepsy treatment, the initial dose is 75 mg twice daily, with a maximum of 600 mg per day. For fibromyalgia, the dose ranges from 300 to 450 mg per day. Pregabalin can be taken with or without food.

Side Effects

Common side effects include dizziness, drowsiness, dry mouth, blurred vision, weight gain, and edema. Some patients may experience abnormal thinking or mild confusion. If severe side effects such as muscle weakness, breathing difficulties, or allergic reactions occur, seek medical attention immediately.

How to Use

Follow the prescribed dosage and swallow the capsule whole with water. Do not chew or break the capsule. If discontinuation is necessary, gradually reduce the dose over a week to prevent withdrawal symptoms.

Pregnancy & Lactation

Gabarol 50 falls under Pregnancy Category C, meaning it should only be used if the potential benefits outweigh the risks. Pregabalin may be excreted in breast milk, so it should only be used by nursing mothers if a doctor deems it necessary.

Precautions and Warnings

Do not suddenly stop taking Gabarol 50, as it may lead to withdrawal symptoms such as nausea, headache, and insomnia. Patients with kidney impairment should use the medication cautiously, as it is primarily eliminated through the kidneys. Pregabalin may cause an increase in creatine kinase levels, leading to muscle pain or weakness in rare cases.

Safety Information

Avoid alcohol and sedatives while taking Gabarol 50, as it may enhance drowsiness and dizziness. Caution is advised when performing activities requiring mental alertness, such as driving or operating heavy machinery. Patients with a history of substance abuse should use it under strict medical supervision due to the risk of dependency.

Indications

Gabarol 50 is indicated for neuropathic pain management, post-herpetic neuralgia, adjunctive epilepsy treatment, fibromyalgia, and nerve pain associated with spinal cord injuries.

Pharmacology

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing calcium influx and derve excitability. This action relieves pain and reduces seizure frequency. Pregabalin has a high bioavailability of ≥90% and is eliminated primarily through the kidneys.

Therapeutic Class

Adjunct anti-epileptic drugs.

Storage Conditions

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

3 FAQ

1. Can Gabarol 50 be taken for anxiety?
Although not its primary indication, Pregabalin is sometiPregabalinibed off-label for anxiety disorders. Consult a doctor before use.

2. How long does Gabarol 50 take to work?
Some patients may experience relief within a few days, but full benefits may take weeks, depending on the treated condition.

3. Can Gabarol 50 cause weight gain?
Yes, weight gain is a possible side effect due to increased appetite and fluid retention. Maintaining a balanced diet and regular exercise can help manage weight.

Disclaimer

This information is for educational purposes only and should not replace medical advice. Always consult a healthcare provider before starting or stopping any medication.

 

 

 

 

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