Generic:

Clobetasol Propionate

Description:

Exovate 10 Ointment is a topical medication manufactured by Beximco Pharmaceuticals Ltd. It contains Clobetasol Propionate 0.05%, a highly potent corticosteroid, used to treat a variety of severe inflammatory skin conditions.

Benefits:

Exovate 10 Ointment provides relief from symptoms of inflammation, itching, and redness associated with skin conditions like psoriasis, lichen planus, and discoid lupus erythematosus.

Ingredients:

Active ingredient: Clobetasol Propionate 0.05%.

Uses and Doses:

Adults, elderly, and children over 1 year: Apply a thin layer of Exovate 10 Ointment to affected areas twice daily. Treatment should not exceed two consecutive weeks. For children, limit use to five days and review weekly.

Side Effects:

Common side effects include a burning or stinging sensation, itching, and skin thinning. Prolonged use may lead to Cushing’s syndrome in infants and adults.

How to Use:

Apply a thin layer of the ointment to the affected area, rubbing it gently into the skin. For resistant lesions, occlusion may enhance the effect, but should only be done overnight. Avoid exceeding a total of 50g per week.

Pregnancy & Lactation:

Use during pregnancy or breastfeeding should be considered only if the benefit outweighs the potential risks. It is unclear whether Clobetasol Propionate is excreted in breast milk.

Precautions and Warnings:

Avoid using it on the face for more than five days and keep it away from the eyes. Prolonged use or over-occlusion can lead to skin infections or systemic toxicity.

Safety Information:

This ointment should not be used on areas affected by rosacea, acne vulgaris, perioral dermatitis, or untreated skin infections.

Indications:

Exovate 10 Ointment is indicated for inflammatory skin conditions such as psoriasis, recalcitrant dermatoses, lichen planus, and discoid lupus erythematosus that have not responded well to less potent steroids.

Pharmacology:

Clobetasol Propionate acts by reducing inflammation, itching, and vasoconstriction. It inhibits the release of inflammatory mediators like cytokines and prevents the metabolism of arachidonic acid, providing relief from symptoms.

Therapeutic Class:

Other Topical Corticosteroids.

Storage Conditions:

Store below 30°C, protected from light and moisture. Keep out of reach of children.

FAQs:

Q1: What conditions does Exovate 10 Ointment treat?
A: Exovate 10 Ointment treats psoriasis, lichen planus, discoid lupus erythematosus, and other conditions that don’t respond to weaker steroids.

Q2: How long can I use Exovate 10 Ointment?
A: Treatment should not exceed two weeks for adults. For children, use should be limited to five days.

Q3: Can I use Exovate 10 Ointment on my face?
A: It should be used on the face with caution, and only for up to five days. Avoid contact with the eyes.

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