Generic
Esomeprazole Magnesium Trihydrate

Description
Esoral 40 is a proton pump inhibitor (PPI) containing Esomeprazole 40mg, used to reduce stomach acid production. It treats acid reflux, GERD, peptic ulcers, Zollinger-Ellison syndrome, and H. pylori infections effectively. The medication helps heal and maintain erosive esophagitis and prevents the recurrence of ulcers.

Benefits
Esoral 40 relieves chronic heartburn, acid reflux, and indigestion by controlling stomach acid levels. It promotes the healing of damaged esophageal tissue caused by excessive acid production and prevents ulcer formation due to NSAID use. It is also used as part of triple therapy for H. pylori eradication.

Ingredients
Each capsule contains Esomeprazole Magnesium Trihydrate 40mg as the active ingredient and excipients that improve its stability and absorption.

Uses and Doses
Esoral 40 treats Gastroesophageal Reflux Disease (GERD), erosive esophagitis, duodenal ulcers, gastric ulcers, Zollinger-Ellison syndrome, and acid-related dyspepsia. The usual dose is 20mg to 40mg once daily. For H. pylori eradication, 40 mg is taken once daily for 10 days with Amoxicillin and Clarithromycin. In severe cases, IV injections are used.

Side Effects
Common side effects include headache, nausea, diarrhea, abdominal pain, flatulence, and constipation. Long-term use may lead to vitamin B12 deficiency, osteoporosis-related fractures, and kidney issues. Consult a doctor if any severe reactions occur.

How to Use
Take Esoral 40 once daily, at least 1 hour before a meal. Swallow the capsule whole with water. If unable to swallow, open the capsule and mix the granules with applesauce. Do not chew or crush. If using an IV form, it should be administered by a healthcare professional.

Pregnancy & Lactation
Esomeprazole is classified as pregnancy category B by the FDA. While no significant risks have been identified, it should only be used if necessary. There is insufficient data on its excretion in breast milk, so lactating mothers should consult a doctor before use.

Precautions and Warnings
Before treatment, rule out gastric cancer if ulcers are suspected. Long-term use may increase the risk of fractures and vitamin B12 deficiency. If taken with antibiotics, follow the prescribed instructions carefully. Patients with liver disease should use it cautiously.

Safety Information
Without medical advice, esoral 40 should not be taken with certain antifungals, antiretroviral drugs, or blood thinners. Avoid alcohol and smoking, as they can worsen acid reflux symptoms. Long-term users should undergo periodic medical monitoring.

Indications
Esoral 40 is prescribed for GERD, erosive esophagitis, Zollinger-Ellison syndrome, gastric ulcers, NSAID-associated ulcers, and H. pylori eradication.

Pharmacology
Esomeprazole inhibits the H+/K+-ATPase enzyme in gastric parietal cells, blocking acid secretion. It provides better acid control than racemic proton pump inhibitors and remains effective for over 24 hours after a single dose.

Therapeutic Class
Proton Pump Inhibitors (PPIs).

Storage Conditions
Store in a cool, dry place below 30°C, protected from moisture and direct sunlight. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

1. How long does Esoral 40 take to work?
It starts working within 1 hour, but relief from acid reflux symptoms may take 3 to 4 days.

2. Can Esoral 40 be used long-term?
Yes, but a doctor should monitor long-term use due to potential bone and vitamin deficiencies.

3. Is Esoral 40 safe for daily use?
It is commonly prescribed daily, but a healthcare provider should determine the treatment duration.

Disclaimer

This content is for informational purposes only and does not replace medical advice. Always consult a healthcare professional before using any medication.

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