Generic

Esomeprazole Magnesium Trihydrate

Description

Esoral 20 is a proton pump inhibitor (PPI) containing Esomeprazole Magnesium, primarily prescribed to manage gastric acidity and symptoms related to GERD, erosive esophagitis, and ulcers. Manufactured by Eskayef Pharmaceuticals Ltd, this 20mg tablet ensures effective acid suppression and improved absorption with an enteric-coated design for optimized delivery.

Benefits

Esoral 20 offers relief from symptoms of chronic heartburn and GERD, supports the healing and maintenance of erosive esophagitis and assists in eradicating Helicobacter pylori infections when combined with other medications. It also addresses conditions like Zollinger-Ellison syndrome, dyspepsia, and both duodenal and gastric ulcers.

Ingredients

Each Esoral 20 tablet contains 20 mg of Esomeprazole Magnesium, designed as an enteric-coated pellet formulation to ensure targeted release and absorption.

Uses and Doses

• Healing of Erosive Esophagitis: 20 mg or 40 mg once daily for 4–8 weeks.
• Maintenance of Healing: 20 mg once daily.
• GERD: 20 mg once daily for 4 weeks, with possible extension.
• H. Pylori Eradication: 40 mg once daily for 10 days in combination therapy.
• Zollinger-Ellison Syndrome: 20-80 mg once daily, dose adjusted per individual.
• Acid-related Dyspepsia: 20-40 mg once daily for 2–4 weeks.
• Duodenal Ulcer: 20 mg once daily for 2–4 weeks.
• Gastric Ulcer: 20-40 mg once daily for 4–8 weeks.

Side Effects

Reported side effects include headache, diarrhea, nausea, flatulence, abdominal pain, and constipation. Less common effects include skin rash, dizziness, dry mouth, and rare instances of hypersensitivity reactions.

How to Use

Take Esoral 20 as directed by a healthcare provider, typically one hour before a meal. Tablets should be swallowed whole, without crushing or chewing. For delayed-release suspensions, mix with water as instructed and consume immediately. Intravenous administration should be done slowly over at least 3 minutes for effectiveness.

Pregnancy & Lactation

Classified under FDA pregnancy category B, Esomeprazole should be used during pregnancy only if necessary. Nursing mothers should consult healthcare providers as it is unclear if Esomeprazole passes into breast milk.

Precautions and Warnings

Patients should rule out gastric cancer before beginning treatment with Esomeprazole. Follow dosage instructions carefully, and consult a doctor before use if you experience any persistent stomach issues.

Safety Information

Store Esoral 20 in a dry place below 30°C, away from light and moisture. Keep out of reach of children and check for any visible changes before use.

Indications

Esoral 20 is prescribed for GERD, erosive esophagitis, H. pylori eradication, Zollinger-Ellison syndrome, dyspepsia, and duodenal and gastric ulcers.

Pharmacology

Esomeprazole functions by inhibiting the H+/K+-ATPase enzyme in gastric parietal cells, reducing gastric acid secretion. This S-isomer of Omeprazole is designed for enhanced bioavailability and acid control.

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Store at a temperature not exceeding 30°C in a dry place, protected from light and moisture. Ensure it is kept out of children's reach.

3 FAQ

1. What is Esoral 20 used for?
   Esoral 20 is used to treat conditions caused by excess stomach acid, including GERD, erosive esophagitis, and duodenal ulcers.
2. Can Esoral 20 be taken during pregnancy?
   Esoral 20 is classified as pregnancy category B. Consult a healthcare provider before using it during pregnancy.
3. How should Esoral 20 be stored?
   Store Esoral 20 in a dry, cool location, away from light, and moisture, and out of children’s reach.

Disclaimer

This information is provided for educational purposes and should not replace professional medical advice. Always consult a healthcare provider for diagnosis and treatment.

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