Generic Description Duocard 10 is a prescription medication containing Cilnidipine 10mg, a calcium channel blocker used primarily for hypertension management. ACME Laboratories Ltd. produces it and helps reduce blood pressure by relaxing blood vessels and controlling nerve activity that regulates blood pressure levels.

Benefits Duocard 10 is used for hypertension treatment and end-organ protection, especially in patients with diabetes and chronic kidney disease. It reduces blood pressure by dilating blood vessels, decreasing heart rate, and preventing excessive sympathetic nerve activity. It minimizes the risk of cardiovascular complications, including stroke, heart attack, and kidney damage.

Ingredients Active ingredient: Cilnidipine 10mg Excipients: Microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, hypromellose, titanium dioxide, and other pharmaceutical additives.

Uses and Doses

• Adults: Recommended dosage is 5-10 mg once daily after breakfast—maximum dose: 20 mg daily.
• Elderly: Start with 5 mg daily, as they may be more prone to hypotension.
• Pediatrics: Safety in children has not been established.

Side Effects Common side effects include dizziness, hot flashes, headaches, low blood pressure, palpitations, peripheral edema, increased urination frequency, lethargy, eye pain, and depression. If any severe reactions occur, immediate medical consultation is necessary.

How to Use: Take one tablet daily after breakfast with water. Swallow the tablet whole without crushing or chewing. Always follow the doctor’s prescription and avoid skipping doses.

Pregnancy & Lactation

• Pregnant women: Cilnidipine should be avoided due to potential fetal risks.
• Lactating mothers: Not recommended during breastfeeding. If necessary, breastfeeding should be discontinued while taking this medication.

Precautions and Warnings

• Use with caution in patients with severe liver disease.
• Patients with a history of severe adverse reactions to calcium channel blockers should be monitored.
• Gradual dose reduction is necessary when discontinuing to avoid rebound hypertension.

Safety Information

• Do not take if allergic to Cilnidipine or any excipients.
• Avoid conditions like cardiogenic shock, unstable angina, recent myocardial infarction, and severe aortic stenosis.
• Avoid alcohol consumption as it may intensify side effects.

Indications Duocard 10 is prescribed for hypertension management and end-organ protection in high-risk individuals, including elderly patients and those with diabetes or kidney disease.

Pharmacology Cilnidipine is a dual L-type and N-type calcium channel blocker. It prevents calcium entry into vascular smooth muscle cells, leading to vasodilation and lower blood pressure. Unlike other calcium channel blockers, it also blocks sympathetic nerve activity, reducing heart rate spikes and stress-induced hypertension.

Therapeutic Class is Classified under calcium channel blockers, specifically dihydropyridine derivatives.

Storage Conditions

• Store below 30°C.
• Protect from light and moisture.
• Keep out of reach of children.

3 FAQ 1. Can I take Duocard 10 on an empty stomach? No, it should be taken after breakfast to reduce the risk of dizziness and low blood pressure.

2. How long does Duocard 10 take to work? It typically starts working within a few hours, but full effects on blood pressure may take a few weeks.

3. Can I stop taking Duocard 10 suddenly? No, abrupt discontinuation can cause a rebound increase in blood pressure. Always consult a doctor before stopping.

Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult a healthcare provider before starting or stopping any medication.

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