Generic

Doxiva 100 ml contains Doxophylline 100 mg, a bronchodilator used to treat asthma, COPD, and bronchospasms.

Description

Doxiva 100 ml is a methylxanthine derivative syrup that acts as a bronchodilator, helping to relax airway muscles and improve airflow. It is specifically designed for treating chronic obstructive pulmonary disease (COPD), bronchial asthma, and respiratory conditions associated with bronchospasms. Unlike traditional theophylline, Doxophylline has a safer profile with fewer cardiovascular and neurological side effects.

Benefits

Doxiva 100 ml effectively opens airways, reduces inflammation, and improves lung function, making it beneficial for individuals with chronic respiratory conditions. Compared to other bronchodilators, it provides long-lasting relief and has fewer side effects. The medication helps manage shortness of breath, wheezing, and chest tightness.

Ingredients

Each 5 ml of syrup contains 100 mg of doxophylline, a selective phosphodiesterase (PDE-4) inhibitor that relaxes the bronchial smooth muscles and reduces lung inflammation.

Uses and Doses

Doxiva 100 ml is prescribed for COPD, bronchial asthma, and bronchospasms.

• Adults: 10 ml syrup two or three times daily or as prescribed by a physician.
• Children over 12 years: 10 ml syrup two or three times daily.
• Children 6-12 years: 6-9 mg/kg body weight twice daily.
• If the required daily dose is 400 mg, The SR (sustained release) version may be taken once daily.

Side Effects

Doxiva 100 ml is well tolerated, but some users may experience nausea, vomiting, headache, stomach discomfort, heartburn, or dizziness. Serious side effects are rare but should be reported to a doctor.

How to Use

Shake the bottle well before use. To reduce stomach irritation, take Doxiva with or after meals. Use the measuring cup provided to ensure an accurate dose. Follow the prescribed dosage and do not exceed the recommended limit.

Pregnancy & Lactation

Animal studies indicate that Doxophylline does not harm the fetus, but its safety in human pregnancies is not well established. It should only be used if necessary. Doxiva 100 ml is contraindicated for breastfeeding mothers, as its presence in breast milk may affect the infant.

Precautions and Warnings

Patients with liver disease, heart failure or those taking erythromycin, chlortetracycline, lincomycin, allopurinol, cimetidine, propranolol, or influenza vaccines may require a lower dose due to slower drug clearance. Smokers and individuals on phenytoin or anticonvulsant therapy may need a higher dose due to increased metabolism.

Safety Information

Avoid taking Doxiva 100 ml with other xanthine derivatives, caffeine-containing foods, or ephedrine, as they may cause unwanted effects. Always consult a doctor before combining it with other medications.

Indications

Doxiva 100 ml is indicated for treating COPD, asthma, and bronchospasms. It relieves airway obstruction, improves breathing, and prevents respiratory distress symptoms like wheezing, coughing, and breathlessness.

Pharmacology

Doxophylline selectively inhibits phosphodiesterase-4 (PDE-4), leading to bronchial muscle relaxation and reduced inflammation. Unlike theophylline, it has a lower affinity for adenosine A1 and A2 receptors, reducing its effect on the central nervous system and the heart. Additionally, it suppresses platelet-activating factor (PAF) and leukotrienes, further reducing lung inflammation.

Therapeutic Class

Bronchodilator / Methylxanthine Derivative

Storage Conditions

Store in a cool, dry place away from light and heat. Keep the bottle tightly closed and out of the reach of children.

FAQ

1. Can Doxiva 100 ml be taken with food?
Yes, taking Doxiva with or after meals is recommended to minimize stomach irritation.

2. How long does it take for Doxiva 100 ml to work?
Doxiva starts working within an hour, providing relief for several hours.

3. Can I take Doxiva 100 ml while using other asthma medications?
To avoid potential interactions, consult a doctor before combining it with other bronchodilators or steroid inhalers.

Disclaimer

This information is for educational purposes only. Always consult a healthcare professional before using Doxiva 100 ml, especially if you are pregnant, breastfeeding, or have an underlying medical condition.

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