Generic
Doxophylline

Description
Doximar 400 is a bronchodilator used to treat respiratory conditions such as COPD, bronchial asthma, and bronchospasm. It relaxes bronchial smooth muscles to improve breathing.

Benefits
Doximar relieves bronchospasms, reduces airway resistance, and enhances respiratory function, making it practical for managing chronic respiratory diseases.

Ingredients
Each tablet contains 400 mg of Doxophylline as the active ingredient.

Uses and Doses
Doximar 400 is indicated for treating COPD, bronchial asthma, and bronchospasms.

• Adults: 400 mg two to three times daily or as the physician prescribes.
• Elderly: 200 mg two to three times daily.
• Children (over 12 years): 10 ml syrup or 200 mg tablet two to three times daily.
• Children (6-12 years): 6-9 mg/kg body weight twice daily.

The dosage may vary depending on the severity of the condition and should be determined by a physician.

Side Effects
Common side effects include headache, nausea, vomiting, insomnia, tachycardia, abdominal pain, heartburn, shortness of breath, irritability, and hyperglycemia.

How to Use
Doximar tablets should be taken orally with water. Follow the physician’s prescription for dosage and administration timing.

Pregnancy & Lactation
Studies indicate that Doxophylline does not harm fetal development in animal studies, but limited human data suggest caution. It should only be used during pregnancy if the benefits outweigh the risks. Doxophylline is contraindicated during lactation.

Precautions and Warnings
Patients with liver disease, congestive heart failure, or those taking certain medications such as erythromycin and cimetidine may require dose adjustments due to delayed drug clearance. Smokers and patients on anticonvulsants may need higher doses due to increased clearance rates.

Safety Information
Doximar should not be used with other xanthine derivatives or caffeine-containing products. It should also be avoided when administered with erythromycin, propranolol, and vaccines that reduce hepatic clearance.

Indications
Doximar is indicated for treating COPD, bronchial asthma, and bronchospasm.

Pharmacology
Doxophylline, a bronchodilator, relaxes bronchial smooth muscles by inhibiting phosphodiesterase 4. Unlike Theophylline, it has a lower affinity for adenosine receptors, enhancing its safety profile.

Therapeutic Class
Bronchodilators, Methyl xanthine derivatives

Storage Conditions
Store in a cool and dry place, protected from light. Keep out of reach of children.

3 FAQ

1. Can Doximar 400 be taken with caffeine?
   Avoid caffeine-containing foods or drinks while on Doximar, as it may increase side effects.
2. Is Doximar safe during pregnancy?
   Use only if the potential benefit outweighs the risk. Consult a doctor before use.
3. Can children under six use Doximar?
   No safety and effectiveness in children under six have been established.

Disclaimer
This information is for educational purposes and should not replace professional medical advice. Always consult a doctor for treatment guidance.

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