Generic

Naproxen Sodium + Esomeprazole Magnesium
Dinovo 375/20 combines Naproxen Sodium and Esomeprazole Magnesium to address inflammatory pain while reducing the risk of NSAID-induced gastric ulcers.

Description

Dinovo 375/20 is a dual-action tablet containing enteric-coated Naproxen for pain relief and Esomeprazole, a proton pump inhibitor, to protect the stomach from acid-related damage.

Benefits

This medication effectively relieves inflammation and pain associated with arthritis, reduces gastric ulcer risks in patients using NSAIDs, and improves the quality of life for chronic conditions.

Ingredients

Each tablet contains Naproxen Sodium 375 mg and Esomeprazole Magnesium 20 mg, ensuring effective pain relief and stomach protection.

Uses and Doses

Dinovo is used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis. The usual adult dosage is one tablet twice daily, but the dosage for adolescents depends on body weight.

Side Effects

Common side effects include nausea, headache, diarrhea, indigestion, flatulence, stomach pain, and flu-like symptoms. Contact a doctor if symptoms worsen.

How to Use

Swallow the tablet whole, without chewing or crushing, at least 30 minutes before meals. Always follow your doctor’s recommendations for dosage and duration.

Pregnancy & Lactation

Dinovo 375 is classified under Pregnancy Category C. It should be avoided during late pregnancy due to the risk of premature ductus arteriosus closure. Nursing mothers should not use this medication.

Precautions and Warnings

Patients with cardiovascular disease, fluid retention, or heart failure should use this medication cautiously. Avoid concurrent use with other NSAIDs or warfarin due to potential risks.

Safety Information

Avoid splitting or dissolving the tablet. Do not use it without medical advice if you have a history of ulcers or bleeding disorders or are taking other medications.

Indications

Dinovo is indicated for pain relief in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and prevention of NSAID-related gastric ulcers.

Pharmacology

Naproxen inhibits prostaglandin synthesis to relieve pain, while Esomeprazole blocks acid production in the stomach by targeting H+/K+ ATPase enzymes.

Therapeutic Class

Rheumatoid Arthritis Drugs, Osteoarthritis Drugs, Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.

3 FAQ

1. Can I use Dinovo 375 for general pain relief?
Yes, but it is primarily indicated for arthritis-related pain. Consult your doctor for other pain relief needs.

2. Can I take Dinovo with food?
Yes, take it with food to reduce stomach upset.

3. What should I do if I miss a dose?
Take the missed dose as soon as you remember unless it’s close to the next dose. Avoid double dosing.

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